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Search: Posts Made By: Lani
Forum: her2group 04-10-2018, 05:15 PM
Replies: 0
Views: 863
Posted By Lani
for those wuth her+ brain mets--new clinical trial opened

high dose trastuzumab with pertuzumab and atezolizumab ( anti-PDL1 immunotherapy) in patients with HER2+ CNS disease--pi Nancy Lin,
Dana Farber.
Forum: her2group 03-22-2018, 02:20 AM
Replies: 3
Views: 1,505
Posted By Lani
Three-in-one molecule shows promise in her2+ bc

Three-in-one molecule shows promise in helping certain breast cancer patients
A newly designed three-part molecule could be the one answer patients with a certain form of breast cancer are looking...
Forum: her2group 02-14-2018, 12:52 PM
Replies: 1
Views: 2,109
Posted By Lani
Arrow biosimilar herceptin "progress"

HEALTH NEWSFEBRUARY 13, 2018 / 3:38 PM / A DAY AGO
Drug copies ready to take next bite out of Roche's cancer sales
Ben Hirschler

LONDON (Reuters) - European oncologists will soon get their hands...
Forum: her2group 02-09-2018, 07:04 PM
Replies: 1
Views: 2,177
Posted By Lani
Thumbs up for frail or elderly Stage IVs, a gentler more effective treatment

PUBLIC RELEASE: 9-FEB-2018
Soft chemotherapy is very effective in older patients when added to targeted treatment in an aggressive breast cancer subtype
EUROPEAN ORGANISATION FOR RESEARCH AND...
Forum: her2group 02-03-2018, 03:00 AM
Replies: 0
Views: 2,293
Posted By Lani
Thumbs up intrathecal herceptin fir leptomemgeal metasis of her2+ breast cancer reviews

Breast Cancer Res Treat. 2018 Feb 1. doi: 10.1007/s10549-018-4684-3. [Epub ahead of print]
Intrathecal trastuzumab in the management of HER2+ breast leptomeningeal disease: a single institution...
Forum: her2group 01-30-2018, 07:12 AM
Replies: 4
Views: 2,379
Posted By Lani
Exclamation Stealth 22% price rise on herceptin took place in July!

https://www.linkedin.com/pulse/fake-news-genentech-raises-price-herceptin-227-riccio-rph-bcop


FAKE NEWS: Genentech raises price of Herceptin by 22.7%
Published on June 7, 2017

Lawrence...
Forum: her2group 01-27-2018, 08:26 PM
Replies: 0
Views: 2,377
Posted By Lani
Thumbs up !!Up to the minute remarkable news for those with brain mets or lepto-meningeal mets

Even though a case report (one-off) it augurs well!!

BMC Cancer. 2018 Jan 25;18(1):97. doi: 10.1186/s12885-018-3994-5.
Efficacy of T-DM1 for leptomeningeal and brain metastases in a HER2 positive...
Forum: her2group 01-25-2018, 11:00 AM
Replies: 4
Views: 2,558
Posted By Lani
Angry Michka has earned her wings (back in 2017)

received this today:

Lani from her2support
It's terribly difficult for me to answer: my Wife, Michele Berman is dead last december the 5th.
My english is poor and I have been in an hospital...
Forum: her2group 01-12-2018, 02:41 PM
Replies: 0
Views: 2,542
Posted By Lani
Lightbulb FDA grants regular approval to pertuzumab 4 adjuvant treatment of HER2+ bc

FDA grants regular approval to pertuzumab for adjuvant treatment of HER2-positive breast cancer



On December 20, 2017, the Food and Drug Administration granted regular approval to...
Forum: her2group 01-12-2018, 02:36 PM
Replies: 1
Views: 2,442
Posted By Lani
has this Stanford researcher stolen my puppy dog analogy???

JANUARY 8, 2018
Stanford mechanical engineers give breast cancer research a boost
Stanford researchers say one way to solve the mystery of why some breast cancers are more likely to spread could...
Forum: her2group 01-09-2018, 12:29 PM
Replies: 0
Views: 2,703
Posted By Lani
Thumbs up important advance in understanding ER her2 breast cancer

PUBLIC RELEASE: 9-JAN-2018
UC researchers find protein that mediates formation of HER2-driven breast cancer
UNIVERSITY OF CINCINNATI ACADEMIC HEALTH CENTER

SHARE PRINT E-MAIL...
Forum: her2group 12-24-2017, 08:13 PM
Replies: 4
Views: 2,735
Posted By Lani
Re: Bio similars to Herceptin-are THEY fully humanized????

DESCRIPTION

Ogivri (trastuzumab-dkst) is a humanized IgG1 kappa monoclonal antibody that selectively binds with high affinity to the extracellular domain of the human epidermal growth factor...
Forum: her2group 12-04-2017, 02:31 AM
Replies: 1
Views: 2,689
Posted By Lani
FDA Approves Biosimilar Trastuzumab for HER+ Breast Cancer

FDA Approvals
FDA Approves Biosimilar Trastuzumab for HER+ Breast Cancer


December 01, 2017


The first biosimilar product that corresponds to trastuzumab (Herceptin, Genentech/Roche) has...
Forum: her2group 11-08-2017, 03:17 PM
Replies: 4
Views: 2,958
Posted By Lani
all her2+ tumors are not created equal (very important paper)

Annals of Surgical Oncology
November 2017, Volume 24, Issue 12, pp 34713474 | Cite as
All HER2-Positive Tumors are not Created Equal
Authors
Authors and affiliations
Elizabeth A....
Forum: her2group 09-13-2017, 10:23 AM
Replies: 1
Views: 2,459
Posted By Lani
Lightbulb future treatment of ER+her2+early bc? tdm1only x12wks vs

vs tdm2+ET x12wks vs herceptin +ETx12 weeks neoadj tx followed by usua; adjuvant care compared in trial:


ORIGINAL REPORTS Breast Cancer
De-Escalation Strategies in Human Epidermal Growth Factor...
Forum: her2group 08-09-2017, 09:57 PM
Replies: 0
Views: 2,837
Posted By Lani
for those with leptomeningeal metastases

Send to
Breast Care (Basel). 2017 Jul;12(3):165-167. doi: 10.1159/000464400. Epub 2017 Jun 26.
Efficacy of Liposomal Cytarabine in the Treatment of Leptomeningeal Metastasis of Breast Cancer....
Forum: her2group 08-05-2017, 07:24 PM
Replies: 0
Views: 2,920
Posted By Lani
for those with her2+ brain mets

Send to
Oncotarget. 2017 Jul 26. doi: 10.18632/oncotarget.19634. [Epub ahead of print]
Trastuzumab distribution in an in-vivo and in-vitro model of brain metastases of breast cancer.
Terrell-Hall...
Forum: her2group 08-03-2017, 10:34 AM
Replies: 3
Views: 3,469
Posted By Lani
Re: neratinib approved for early breast cancer!

bumping thus up as it seems to have caught noone's attention

Study was for one year's treatment after 1 yr herceptin for early stage her2+ bc
Forum: her2group 07-21-2017, 09:09 PM
Replies: 3
Views: 3,469
Posted By Lani
Thumbs up neratinib approved for early breast cancer!

U.S. Food and Drug Administration

FDA News Release

FDA approves new treatment to reduce the risk of breast cancer returning

For Immediate Release

July 17, 2017
Release
Forum: her2group 07-14-2017, 12:34 PM
Replies: 1
Views: 3,204
Posted By Lani
for those with lepto-meningeak metastases

ABSTRACT: Efficacy of Liposomal Cytarabine in the Treatment of Leptomeningeal Metastasis of Breast Cancer
[BreastCare]
Background: Breast cancer is one of the most frequent causes of leptomeningeal...
Forum: her2group 06-29-2017, 09:05 AM
Replies: 35
Views: 13,662
Posted By Lani
Re: Good and Bad News

thanks for checking!
Lani
Forum: her2group 06-28-2017, 05:46 PM
Replies: 35
Views: 13,662
Posted By Lani
Question Re: Good and Bad News

It has been almost 2 weeks since Michka posted. Anyone know if she is
ok?

Lani
Forum: her2group 06-08-2017, 12:34 AM
Replies: 35
Views: 13,662
Posted By Lani
Re: Good and Bad News

Most worrisome is Riccardo Soffietti, MD's warning that having had TDM1 before, during (worst) or after radiation therapy increases the risk of radio- necrosis with radiation therapy (srs or wbr) . ...
Forum: her2group 06-08-2017, 12:24 AM
Replies: 13
Views: 4,849
Posted By Lani
Re: Did you have surgery w/o doing chemo?

If you don't do the therapy before the surgery you will lose the opportunity to find out if the treatment is effective (by seeing the tumor shrink) and be left to wait and wait to see if you break a...
Forum: her2group 06-07-2017, 06:01 PM
Replies: 35
Views: 13,662
Posted By Lani
Re: Good and Bad News

http://meetinglibrary.asco.org/record/138228/edbook#fulltext


Breast Cancer in the Central Nervous System: Multidisciplinary Considerations and Management
Presented Monday, June 5, 2017
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