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Search: Posts Made By: donocco
Forum: her2group 04-17-2019, 12:56 PM
Replies: 124
Views: 16,606
Posted By donocco
Re: Treatment after Kadcyla?

Iain

Very sorry for your loss. She was indeed a very sweet woman.

Paul
Forum: her2group 02-08-2019, 11:03 AM
Replies: 124
Views: 16,606
Posted By donocco
Re: Treatment after Kadcyla?

Jules

I hope other people put in their input but if you can get Herceptin with the Eribulin it would seem the way to go. Im sorry you are having problems with the medical board.

I tell ...
Forum: her2group 02-05-2019, 03:28 PM
Replies: 124
Views: 16,606
Posted By donocco
Re: Treatment after Kadcyla?

Jules

I took a quick glance at DS8201. It is Herceptin combined with Deruxtecan and seems to have a good effect in the phase i studies. I tried to find out what Deruxtecan is and didnt have much...
Forum: her2group 02-03-2019, 10:46 PM
Replies: 124
Views: 16,606
Posted By donocco
Re: Treatment after Kadcyla?

Jules

The Acetaminophen in Co-Codomal has been known to lower platelets but it isnt that common.
Could the low platelets be due to another drug? From the cases I read, when the acetaminphen is...
Forum: her2group 02-02-2019, 12:40 PM
Replies: 124
Views: 16,606
Posted By donocco
Re: Treatment after Kadcyla?

Jules

Epirubicin for all intents and purposes is a form of Adriamycin.It is an Anthracycline chemical and has the same side effects as Adriamycin such as hair loss, mouth sores, low white cell...
Forum: her2group 01-19-2019, 06:40 PM
Replies: 124
Views: 16,606
Posted By donocco
Re: Treatment after Kadcyla?

Juls

Go to google. There were cases in Denmark in 1993 where breast cancer patients who took
390mg Coenzyme Q10 daily had the mets cleared. Interesting. You would think everybody would know od...
Forum: her2group 07-20-2018, 10:29 AM
Replies: 124
Views: 16,606
Posted By donocco
Re: Treatment after Kadcyla?

Juls

About 38 years ago when I was in the Public Health Service I was stationed in Phoenix Arizona. I was so glad to get a transfer from the isolated Indian Reservation.

Anyway I had a...
Forum: her2group 07-19-2018, 11:52 AM
Replies: 124
Views: 16,606
Posted By donocco
Re: Treatment after Kadcyla?

Juls

It is hard to say. I dont know the politics of health care in Scotland. If she is brushing you off that is wrong and immoral. Im sure it is obvious to them you are non-confrontational.
...
Forum: her2group 07-18-2018, 01:29 PM
Replies: 124
Views: 16,606
Posted By donocco
Re: Treatment after Kadcyla?

Jules

I contacted Genentech and it seems my reasoning was basically correct. The Emtansine attached to the Trastuzumab molecule causes the complex to bind tightly yo the receptor allowing a lower...
Forum: her2group 07-17-2018, 07:52 AM
Replies: 124
Views: 16,606
Posted By donocco
Re: Treatment after Kadcyla?

Jules

My wife's daughter is visiting from Texas with the grandkids. Ill have to wait until Wednesday to call Genentech. The point is, the dose of Herceptin in Kadcyla is sufficient to
inhibit...
Forum: her2group 07-14-2018, 12:17 PM
Replies: 124
Views: 16,606
Posted By donocco
Re: Treatment after Kadcyla?

Juls

From what I have read now the Herceptin in Kadcyla is active as an anti-Her2neu medication. Kadcyla has the same FDA warnings for possible left ventricular damage as does Herceptin. Will call...
Forum: her2group 07-14-2018, 11:43 AM
Replies: 124
Views: 16,606
Posted By donocco
Re: Treatment after Kadcyla?

Jules

Ive wondered about that myself the Kadycla -Herceptin as carrier thing. Not even close to being sure. The dose of Hereceptin given weekly is 4mg/kg loading dose then 2 mg/kg weekly IV. Not...
Forum: her2group 07-13-2018, 02:27 PM
Replies: 124
Views: 16,606
Posted By donocco
Re: Treatment after Kadcyla?

Juls

As far as I know Herceptin use has nothing to do with Xeloda. The closest thing would be the combination of Lapatinib 1250mg daily (Lapatanib= Tykerb) plus Xeloda 1000mg/m2 twice a day....
Forum: her2group 07-03-2018, 05:09 PM
Replies: 124
Views: 16,606
Posted By donocco
Re: Treatment after Kadcyla?

Juls

What about Perjeta. I dont know if alone it will do anything but Ill see what I can find.
Perhaps Perjeta plus Lapatinib. Neryx (Neratinib) might work better but I kind of doubt NICE
has...
Forum: her2group 07-02-2018, 10:05 AM
Replies: 124
Views: 16,606
Posted By donocco
Re: Treatment after Kadcyla?

Juls

I dont think so. Not if you are Her 2 Neu positive. I dont see how it could be. Even if you were just ER positive an Aromatase inhibitor by itself probably wouldnt be enough unless you are...
Forum: her2group 06-19-2018, 05:33 PM
Replies: 124
Views: 16,606
Posted By donocco
Re: Treatment after Kadcyla?

The angiogenesis inhibiting effect of copper reduction is general. Normal cells in your body also use copper but it seems that copper reduction is not that toxic to normal cells. Perhaps they are far...
Forum: her2group 06-19-2018, 12:01 PM
Replies: 124
Views: 16,606
Posted By donocco
Re: Treatment after Kadcyla?

Juls

You mentioned being told that Aromase Inhibitors are never to be given with Kadcyla.
Im curious where these oncologists got this info. Kadcyla is Herceptin with a chemo drug attached to...
Forum: her2group 06-13-2018, 01:26 PM
Replies: 124
Views: 16,606
Posted By donocco
Re: Treatment after Kadcyla?

Juls

Look up the work of Dr Linda Vahdut. She is a physician not an alternative practioner. She has been treating triple negative breast cancer with a copper chelator known as Ammonium...
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