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Forum: Articles of Interest 04-11-2007, 07:39 AM
Replies: 1
Views: 2,606
Posted By heblaj01
This Australian group of researchers has done a...

This Australian group of researchers has done a lot of interesting work on vitamin E succinate in the lab.

For human applications at least two possible problems must be clarified:
1. In vivo it...
Forum: Articles of Interest 04-08-2007, 11:20 PM
Replies: 2
Views: 1,566
Posted By heblaj01
Joy, For lack of sufficient knowledge I am...

Joy,
For lack of sufficient knowledge I am sorry I can't answer your question but here is a 2006 article on second cancers:...
Forum: her2group 04-06-2007, 06:38 PM
Replies: 10
Views: 2,589
Posted By heblaj01
Most of the recommandations (treatment,diet...)...

Most of the recommandations (treatment,diet...) seem to make sense in the CAAT web site (except perhaps the use of fructose).
What is lacking are direct references to the publications of clinical...
Forum: Articles of Interest 04-06-2007, 09:41 AM
Replies: 2
Views: 1,566
Posted By heblaj01
TGF-beta induced by chemo &/or radiotherapy :bad news & good news

The mice study linked below appears to confirm suspicions that chemo & radiation may induce TGF-beta as a side effect which has been found to be one of the factors promoting metastases in metastatic...
Forum: her2group 04-05-2007, 09:39 PM
Replies: 20
Views: 3,103
Posted By heblaj01
Barbara, Please ask Dr Pegram what he thinks of...

Barbara,
Please ask Dr Pegram what he thinks of the Tykerb+ Herceptin combo for advanced breast cancer based in particular on the very positive comments of the phase 2 trials in the neo adjuvant...
Forum: her2group 04-04-2007, 09:16 PM
Replies: 2
Views: 1,259
Posted By heblaj01
Laurie, There are wide variations in absorption...

Laurie,
There are wide variations in absorption of CoQ10 depending on the type of pill: powder,softgel, Q-gel...
So taking one that has high absorption, reduces the number of pills necessary to...
Forum: Articles of Interest 04-03-2007, 01:19 PM
Replies: 0
Views: 1,386
Posted By heblaj01
Anti-inflammatory drugs prevent heart damage induced by Doxorubicin in mice

Semi synthetic flavonoid monoHER has been shown in preclinical studies dating back to at least 2003 to prevent heart damage caused by Doxorubicin without reducing its efficacy. It has been speculated...
Forum: her2group 04-01-2007, 06:45 PM
Replies: 20
Views: 3,276
Posted By heblaj01
Regarding the private funding of research on...

Regarding the private funding of research on unpatentable drugs mentioned in above posts maybe this Forum could follow the example of some other similar organizations who helped fund part of some...
Forum: Articles of Interest 03-30-2007, 11:11 PM
Replies: 1
Views: 1,309
Posted By heblaj01
EGCG green tea extract as a possible inhibitor of IGF-IR activity

In this mice study , EGCG prevents the receptor for IGF-I from being activated,
a function regarded as important in the previous post on Tykerb.
...
Forum: her2group 03-30-2007, 05:15 AM
Replies: 5
Views: 1,261
Posted By heblaj01
Robyn, If you want to go the EAP way of getting...

Robyn,
If you want to go the EAP way of getting access to Tykerb, the first site in Canada is in Oshawa Ontario:
Lakeridge Health Oshawa hospital. <TABLE border=1><TBODY><TR><TD>1 Hospital Court,...
Forum: her2group 03-28-2007, 11:30 PM
Replies: 1
Views: 1,297
Posted By heblaj01
Larger trial confirms RF ablation as option for lung cancer (vs radiotherapy)

This larger trial shows comparable if not better results than radiotherapy for both primary & metastatic lung cancer & with less severe side effects.
...
Forum: her2group 03-26-2007, 06:20 AM
Replies: 37
Views: 3,443
Posted By heblaj01
Years ago I listened on TV to the interview of a...

Years ago I listened on TV to the interview of a well known French oncologist on a tour of lectures in North America. He said (& this was before many of the new treatments were discovered):I treat &...
Forum: Inflammatory Breast Cancer 03-24-2007, 09:13 AM
Replies: 1
Views: 2,668
Posted By heblaj01
Updated IBC info in Evidence-based Breast Cancer Treatment Guidance(8 Feb 07)

The updates are preceded by : (new) in
http://ibcwatch.evidencewatch.com/
Forum: Articles of Interest 03-24-2007, 06:38 AM
Replies: 0
Views: 1,150
Posted By heblaj01
For those fluent in french an excellent info site

The info on this french site is quite extensive (but still comprehensible to the layman) & appears up to date on targeted treatments.

http://www.infocancer.org/ESP/MEDICAMENT/CIBLE/cible.htm
Forum: Articles of Interest 03-23-2007, 04:07 PM
Replies: 3
Views: 1,660
Posted By heblaj01
Hopeful, I wonder if you might be able to get...

Hopeful,
I wonder if you might be able to get Herceptin & low dose Doxil assuming this is the combo you seek.
This combo in normal dosages is already prescribed by some oncs & in low doses for...
Forum: Articles of Interest 03-23-2007, 01:12 PM
Replies: 3
Views: 1,660
Posted By heblaj01
Seven pancreatic cancer patients saved by metronomic chemo & naturopathy

I am posting this article even though it is not related to breast cancer because it involves low dose (metronomic) chemo which has also been tried for BC.
If the 7 cases related in the are article...
Forum: Articles of Interest 03-23-2007, 12:21 PM
Replies: 0
Views: 984
Posted By heblaj01
More effecive,less risky brain surgery at Cincinnati Un. Hospital

http://www.sciencedaily.com/releases/2007/03/070319175902.htm
New Technology Making Brain Tumor Surgery Less Risky
Forum: her2group 03-19-2007, 05:11 PM
Replies: 6
Views: 2,122
Posted By heblaj01
There is no doubt that the results of the Alberta...

There is no doubt that the results of the Alberta lab experiments are impressive. But as much impressive have been the observed side effects on patients treated for acidosis with DCA: severe...
Forum: Articles of Interest 03-19-2007, 05:19 AM
Replies: 6
Views: 2,135
Posted By heblaj01
Roz, The quantity of required oil is very...

Roz,
The quantity of required oil is very small. But if you insist in having it discarded before drinking the wine there are at least two easy ways,
One way is to poor the wine in a container with...
Forum: Articles of Interest 03-18-2007, 10:59 PM
Replies: 2
Views: 1,407
Posted By heblaj01
In this informative link...

In this informative link (http://www.bionovo.com/media/mediaarchives/Bionovo_Breast_Cancer_Research_Treatment.pdf)
besides the original procedure to for the raw extract of BZL101 from the plant one...
Forum: Articles of Interest 03-18-2007, 07:06 PM
Replies: 6
Views: 2,135
Posted By heblaj01
Hopeful, Raisins are said to contain much less...

Hopeful,
Raisins are said to contain much less antioxidants (which probably include resveratrol) than fresh grapes probably as a result to exposition to the sun, air & possibly other processing...
Forum: Articles of Interest 03-18-2007, 12:53 PM
Replies: 2
Views: 1,407
Posted By heblaj01
Thanks Lani, for this is a very interesting post...

Thanks Lani, for this is a very interesting post which may portend a future low toxicity treatment.
The following article where Dr Mary Tagliaferri (co-discoverer of BZL101 with Dr Isaac Cohen ) is...
Forum: Articles of Interest 03-17-2007, 12:08 PM
Replies: 6
Views: 2,135
Posted By heblaj01
Risk from resveratrol in the skin of red grapes...

Risk from resveratrol in the skin of red grapes grown in large scale commercial vineyards is likeky to be very low if not nil.
This is because the level of resveratrol in these grapes is quite low....
Forum: Articles of Interest 03-16-2007, 09:31 PM
Replies: 0
Views: 1,983
Posted By heblaj01
Sulfasalazine reduces glutathione levels in breast cancer cells & boosts Doxorubicin

Sulfasalazine is a drug made up of aspirin & a sulfa antibiotic. It is approved for the treatment of rhumatism.

In the reported cell experiment the reduction in glutathione (an antioxidant present...
Forum: her2group 03-16-2007, 10:16 AM
Replies: 30
Views: 3,271
Posted By heblaj01
Joe, Since in an other post you say that GSK is...

Joe,
Since in an other post you say that GSK is not going to answer many of the questions in this thread which go beyond the FDA appoval criteria, could you get some responses from oncs not tied to...
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