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Search: Posts Made By: Lani
Forum: Inflammatory Breast Cancer 09-03-2007, 03:11 AM
Replies: 3
Views: 2,857
Posted By Lani
downregulation only means it is decreased, not necessarily absent

(although it can be)

In general according to Dr.Mark Pegram, one of the authors of the original article, all her2+ breast cancers have less ER than their measured ER
% would seem to indicate. ...
Forum: Inflammatory Breast Cancer 08-29-2007, 08:55 AM
Replies: 3
Views: 2,857
Posted By Lani
Forum: Inflammatory Breast Cancer 08-29-2007, 08:55 AM
Replies: 3
Views: 2,857
Posted By Lani
complicated new article on the origins/pathways gone awry in Inflammatory BC

ABSTRACT: NF-?B activation in inflammatory breast cancer is associated with oestrogen receptor downregulation, secondary to EGFR and/or ErbB2 overexpression and MAPK hyperactivation [British Journal...
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