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Search: Posts Made By: broccoli
Forum: her2group 02-19-2017, 12:32 PM
Replies: 20
Views: 9,233
Posted By broccoli
Re: Metformin, anything new?

I am in a Metformin study. About a year ago a preliminary analysis of their data showed that there was zero impact on ER- patients, so all ER- patients were taken off the drug (including me). As far...
Forum: her2group 03-14-2016, 12:04 AM
Replies: 9
Views: 8,513
Posted By broccoli
Re: "significantly imroved" 2 yr disease ree survival if 1 yr of neratinib given afte

Seems like it may. See this report: http://www.ascopost.com/News/36358
Forum: her2group 03-03-2016, 01:12 PM
Replies: 19
Views: 6,800
Posted By broccoli
Re: Do you take Metformin?

I just got confirmation from my study coordinator that all ER-/PR- patients are to stop taking Metformin, as it is having no effect on outcome.

Of course what that DOES mean is that they are...
Forum: her2group 02-27-2016, 12:31 PM
Replies: 19
Views: 6,800
Posted By broccoli
Re: Do you take Metformin?

Sarah -- all types of breast cancer were included in the trial.
Forum: her2group 02-27-2016, 11:26 AM
Replies: 11
Views: 4,873
Posted By broccoli
Re: Anyone on Lyrica?

I took (still take, but am weening off of it) gabapentin for nerve pain from several herniated discs. Gabapentin and Lyrica are very similar. My side effects haven't been too objectionable -- the...
Forum: her2group 02-27-2016, 11:00 AM
Replies: 19
Views: 6,800
Posted By broccoli
Re: Do you take Metformin?

I've just heard from a friend on the Metformin trial who had TNBC that all ER-/PR- patients are being dropped from the trial because the latest analysis of the data has shown that Metformin has no...
Forum: her2group 01-21-2016, 05:06 PM
Replies: 12
Views: 5,374
Posted By broccoli
Re: Radiation repercussions almost 10 years later

I received radiation therapy to my left breast in November of 2012. They had me do ABC breathing (assisted breath control) to reduce exposure to my heart -- but at the expense of my lung. I will...
Forum: her2group 01-21-2016, 04:43 PM
Replies: 19
Views: 6,800
Posted By broccoli
Re: Do you take Metformin?

I may or may not be taking Metformin -- I'm participating in a trial to see if it has any effect on breast cancer recurrence. I haven't noticed any side effects, so I may be on a placebo.
Forum: Herceptin / Tykerb 11-24-2015, 11:21 PM
Replies: 8
Views: 10,504
Posted By broccoli
Re: Tykerb/Xeloda Not Working Anymore :(

@waytooyoung - did you check with your study coordinator to see if they could reveal whether you got the placebo or perjeta?

Laura
Forum: her2group 08-25-2015, 10:28 PM
Replies: 1
Views: 2,045
Posted By broccoli
Re: Gabapentin for hot flashes

I discovered by accident that gabapentin reduces hot flashes when my surgeon prescribed it for nerve pain. It also got rid of my insomnia and restless legs. Sometimes I think about going back on it...
Forum: her2group 08-24-2015, 07:04 PM
Replies: 10
Views: 4,607
Posted By broccoli
Re: IT Herceptin needed in Canada

A friend of mine in Toronto was part of a trial in Detroit. The only out of pocket costs she had was travel to Detroit periodically.

-Laura
Forum: her2group 08-23-2015, 08:12 PM
Replies: 10
Views: 4,607
Posted By broccoli
Re: IT Herceptin needed in Canada

You might also want to ask your oncologist about getting into one of the ONT-380 trials. While the one being run out of PMH has previous TDM-1 as an exclusion (which seems odd if the TDM-1 is...
Forum: Herceptin / Tykerb 08-23-2015, 08:03 PM
Replies: 8
Views: 10,504
Posted By broccoli
Re: Tykerb/Xeloda Not Working Anymore :(

OHIP covers Herceptin/Perjeta/Taxol if your previous treatment worked for 6 months or longer. (https://www.cancercare.on.ca/CCO_DrugFormulary/Pages/DfPdfContent.aspx?itemId=290630) You are likely in...
Forum: her2group 02-25-2015, 04:41 PM
Replies: 35
Views: 39,675
Posted By broccoli
Re: ER-/PR- HER2 staging poll

Hi Debbie, was the recurrence detected by a mammogram or by another type of scan?

Just curious.

Thanks! Laura
Forum: her2group 12-20-2014, 10:13 AM
Replies: 18
Views: 4,144
Posted By broccoli
Re: Neoadjuvant Roll Call

Quick update: back to NED. It took 9 months of various scans and exams due to the number of issues and symptoms I've been having, but as of a final MRI on Wednesday night, I can confidently say that...
Forum: her2group 07-27-2014, 08:59 PM
Replies: 10
Views: 2,862
Posted By broccoli
Re: Anyone here in this study?

I'm in one of Dr. Pam Goodwin's Metformin trials (the Canadian doctor mentioned above). I don't know if I'm taking Metformin or a placebo. I know my doctors were guessing I got the real thing because...
Forum: her2group 06-18-2014, 08:35 PM
Replies: 3
Views: 1,671
Posted By broccoli
Re: spots on the palms and soles

I got new "freckles" in strange places during FEC -- the nurse said it was probably the 5FU (the F in FEC), but now I wonder. One thing - I never wore sunscreen during chemo because I never spent any...
Forum: her2group 03-12-2014, 08:13 PM
Replies: 18
Views: 4,144
Posted By broccoli
Re: Neoadjuvant Roll Call

Annnnd... I'm no longer NED. I guess pCR is overrated.
Forum: her2group 02-15-2014, 05:40 PM
Replies: 18
Views: 4,144
Posted By broccoli
Re: Neoadjuvant Roll Call

Coux92 - DCIS tends to be non-responsive to chemo. I have yet to come across a decent explanation for this. I even asked my brainwave medical onc and he couldn't really explain WHY just that that's...
Forum: her2group 02-12-2014, 08:42 PM
Replies: 18
Views: 4,144
Posted By broccoli
Neoadjuvant Roll Call

I'm curious who all had or is having neoadjuvant chemo. For those who have had surgery since chemo, how much cancer was left? How long has it been since surgery?

I had neoadjuvant FEC-D +...
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