Article Vogl, NY: TDM-1 Is a Good Drug, But Better Than WHAT
 

Lani an interesting article from clinical oncology.

http://www.clinicaloncology.com//Vie...887&a_id=21703

Vogl, NY: TDM-1 Is a Good Drug, But Better Than WHAT?

Not sure I understand his reasoning.

Darita

Re: Article Vogl, NY: TDM-1 Is a Good Drug, But Better Than WHAT
 

great article

Vogel, NY is a very welcome contributor to question sessions after presentations at ASCO meetings

He is insightful and down-to-earth and never forgets that results only means as much as they help those suffering.

Yes, Roche (purposely it semms) semms not to have choseb the best treatment for the alternate arm to compare TDM1 to

I hope this does not stop TDM1 from being approved for those it could help

Re: Article Vogl, NY: TDM-1 Is a Good Drug, But Better Than WHAT
 

It is a really interesting article but I felt quite dismissive of the plight of women with metastatic herr2 disease for whom herceptin has not been the golden panacea. I don't think any of us really imagine that TDM1 is that and in that regard pertuzamab is so promising but... For this to be a chronic disease as he says, we need weapons in our arsenal and TDM1 with less side effects is certainly worthwhile at that. It worries me that they see the numbers of her2 women getting metastatic diseases shrinking as adjuvant therapies are more successful that those of us for whom they a not will be left behind. I guess though that they always seem to test the new stuff on us (nothing to lose hey?) first so that will help - apart from most of the vaccines it seems. While Emilia was the first study, Marianne surely must have some prelim results coming and th3resa too.
Still a very interesting and insightful article.

Re: Article Vogl, NY: TDM-1 Is a Good Drug, But Better Than WHAT
 

"NEW" weapons in arsenal, indeed very important, maybe even more important is technology incorporated in these state-of-the-art weapons continuous to be improved upon; so new agents of today,become the foundation for even more efficacious treatments in the future.
According to article, T-DM1 once approved, will be prescribed by many of the ASCO attending oncologists.
http://www.oncbiz.com/blog/2012/06/o...ollowing-asco/

Re: Article Vogl, NY: TDM-1 Is a Good Drug, But Better Than WHAT
 

Interesting article. Thanks for sharing.

Re: Article Vogl, NY: TDM-1 Is a Good Drug, But Better Than WHAT
 

MJ's Hubby;

Glad to read that MJ's latest scan showed NED. Now that you have read this article I hope you discuss with the Onc adding Herceptin to the Tykerb, when you are stage IV the article drives home the point that we should never go without it.

Re: Article Vogl, NY: TDM-1 Is a Good Drug, But Better Than WHAT
 

This doc is a prime example of a nitpicker or bean -counter, forever analyzing , even drugs they are not familiar with. So " scientific ' they end up being " un -scientific ', ignoring the facts . The Internet is both a blessing and a curse , as we try to wade through every ' tom , dick and harrys " opinion. Tyk/xel. is the latest APPROVED combo for Late Stage IV Her2 + Survivors, and makes great sense as a comparator to T DM-1. he wants to do more trials ? w/ taxol ?, navelbine ? how about gemcitabine, platinum salts ?,
This " NY Doc " ( that puts him in the company of thousands , right ? ), sounds just like This FDA. If he isn't using T DM-1 in his practice by this time next year, he won't have many metatstatic Her2 Pts in his practice. Mark my words.