Fire up the flux capacitor...new drug trial for me!
 

Oooh. Probably should have posted this BEFORE the Benadryl drip:)))))
Well,I can still blame the iPad spellchecker.

Im 90 minutes away from my first dose of yet another study drug, mk2206 whIch is an akt inhibitor. It is a small molecule dru, take in pill form, which targets a growth signaling pathway downstream from her2...- as well as some others if I recollect the slide at sabcs correctly.

It's somewhat back to the future for me - this is the trial iwas trying to get into last June, but couldn't because my platelets were too low post TDM1.

It is another phase 1 dose escalation study, but in this case they have already found the MTD and are just expanding participants in at that dose. Unlike the mm302 trial that didn't do much but maybe was just not a high enough dose in my case.

So perhaps there is a reason why this trial was a no-go for me last year..

Although the mk2206 is a targeted therapy, In dthis study it is combined with herceptin and taxol, so in a way that's kinda back to the future too as my initial therapy in 2004 was TCH.


Hoping this will be a killer combo!

Re: Fire up the flux capacitor...new drug trial for me!
 

Sounds like a dynamite combo!!!
Keep us posted every step of the way.
Love,
Karen Z

Re: Fire up the flux capacitor...new drug trial for me!
 

I hope so too - good luck xx

Re: Fire up the flux capacitor...new drug trial for me!
 

It sounds like you are once again a pioneer. Good luck on your latest journey. Take good care of yourself.
Let us know how it goes. I have my fingers crossed for you too.

Re: Fire up the flux capacitor...new drug trial for me!
 

To boldly go where no man (or woman) has gone before!!!!! Good luck with the voyage. Hope you zap those Romulens (sp?) along the way!

Re: Fire up the flux capacitor...new drug trial for me!
 

Chrisy,
Once again I am so thankful for yet another brave woman like you taking the risks so others (even men like me) may eventually benefit from their effort. I am hoping that in this case there are plenty of rewards in store for you. Thank you.
--bird

Re: Fire up the flux capacitor...new drug trial for me!
 

Go, Chrisy! Wishing you speedy results and final destination to NED.
Love
Karen

Re: Fire up the flux capacitor...new drug trial for me!
 

I second all the well wishes. ma

Re: Fire up the flux capacitor...new drug trial for me!
 

Re: Fire up the flux capacitor...new drug trial for me!
 

Great Chrisy!! Best of luck with this new trial for you. Hugs.

Re: Fire up the flux capacitor...new drug trial for me!
 

Go Get'em Chrisy!!

Wishing you a speedy voyage back to NED!!

all the best
caya

Re: Fire up the flux capacitor...new drug trial for me!
 

Thank you Chrisy! You have done so much all ready Gods blessings to you!

Re: Fire up the flux capacitor...new drug trial for me!
 

Flux capacitor?
Romulans?

I knew I loved you guys for a reason! Sci-fi geeks unite!
Go, Chris! While you're zapping Romulans...hope you also catch any cancer beasties trying to "Kling-on" to your healthy self! And, I hope the future has you back to NED soon!
Denise

Re: Fire up the flux capacitor...new drug trial for me!
 

Re: Fire up the flux capacitor...new drug trial for me!
 

Well, if doc can't get the flux capacitor working, I am sure Scotty would be glad to beam you up.
Best of luck on your new journey and a big "thank you" from all of us.
Wishing you the best,
Emelie

Re: Fire up the flux capacitor...new drug trial for me!
 

Flux Capacitator....is that something to cook Potato Balls in??? And you could spell that while on Benedryl???
i am impressed.....hoping this new drug will be your prince....I mean your frog! We know you have to kiss alot of frogs before you find your prince!

Re: Fire up the flux capacitor...new drug trial for me!
 

I'm with the others. You are a rock star! For alot of reasons beginning with being able to type all that technical stuff whilst on Benedryl! I would be sitting there drooling.
Keep the faith.

Re: Fire up the flux capacitor...new drug trial for me!
 

My money is on a good initial whack, finding NED, cutting back to maintenance and holding that course. No dragging anchor this time!

Re: Fire up the flux capacitor...new drug trial for me!
 

Good luck Chrisy, live long and prosper !

Re: Fire up the flux capacitor...new drug trial for me!
 

Prepare for liftoff! You certainly are a trailblazer. I know we all appreciate so much you ladies who are willing and able to do these drug trials and help us get closer and closer to that cure we have all been waiting for. Go get em, Chrisy!!!!! Lots of positive energy being sent your way.