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-   -   The microenvironment in breast cancer progression (https://her2support.org/vbulletin/showthread.php?t=54308)

Hopeful 05-09-2012 06:28 AM

The microenvironment in breast cancer progression
 
http://breast-cancer-research.com/co...df/bcr2912.pdf

Hopeful

gdpawel 06-05-2012 06:39 PM

The microenvironment contributes critically to drug response
 
By examining drug-induced cell death events in native-state 3D (three dimensional) microclusters, the functional profiling platform has the unique capacity to capture stromal, cytokines (chemokines), macrophages, lymphocytes, vascular and inflammatory cell interactions with tumor cells, known to be crucial for clinical response prediction.

The microclusters recapitulate the human tumor environment, while the "3D" advancement recreates the extracellular matrix (metalloproteinases). The platform studies cancer response to drugs within this microenvironment, enabling it to provide clinically relevant predictions to cancer patients. It is this capacity to study human tumor microenvironments that distinguishes it from other platforms in the field.

Ellie F 06-06-2012 02:01 AM

Re: The microenvironment in breast cancer progression
 
Thanks for the additional info and also for your valuable contribution to the board.

Ellie


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