Not HER2 anymore
 

Hello HER2 friends,

I just got the report from my liver biopsy.

ER+ 100% PR 10% and HER2 one + considered not HER2

I am so surprised after 10 years! No wonder Kadcyla stopped working.

Did this happen to anybody?

HER2 and non HER2 tumors at the same time giving me the impression that Kadcyla stopped working when in fact it wiped out the HER2 tumors but had no impact on the other ones?

I was focused on trying to get Pertuzumab in France but it is of no use!

I didn't see my onc yet.

Re: Not HER2 anymore
 

Michka,

That is interesting! I hope Lani or some other propeller-head chimes in on this. What are they proposing for the treatment for the mets?

I am so sorry you are still fighting the beast. You will be in my prayers and please keep us posted.

Re: Not HER2 anymore
 

Sneaky, insidious disease. I'm glad you had the biopsy done. I hope you are offered a new treatment that clobbers the hell out of your lesion(s). You're on the right track now.

Re: Not HER2 anymore
 

Are you still taking an Aromatase inhibitor like Femara?
Hopefully not being HER2+ in your liver makes it easier to fight. What about the bones? same thing? not HER2+???
love Sarah

Re: Not HER2 anymore
 

Michka,

What a surprise! Or a shock.

I know a woman who has two separate breast cancers, both metastatic, one HER-2+ and one not. She's actually doing very well.

Knowledge is power. Now that you know what you're dealing with your treatment can be planned accordingly.

And please stay in our group. You're still our sister, HER-2+ or not.

Love,
Amy