Thanks for the reply. I am taking 100mg caps - two a day. That is half what you are taking. And WAY less than those studies. My Onc wanted me to take 2 twice a day. Maybe I should give it a try and see if I can tolerate 300 or 400mg now (am normally sensative to meds and need less than normal adult dose to take affect on such things as pain and allergy pills - never mind the trouble I had with anesthesia). I started Celebrex right after completing a rough course of chemo and my system was not its normal self!