HER-2 Positive & Triple Negative = Cannabis Intervention
 

Hi, All,
I have been checking in from time to time...things are quite good here.

I just read an article I thought would be of interest in light of the fact patient testimonials are increasingly abundant and positive of the treatment and curative properties of cannabis. It is my fervent hope that cannabis oil, in its proper ratio, will be decriminalized for all those who wish to partake.
And that on a federal level, it will be covered by insurance as a useful tool in the treatment of breast cancer.

We can all look to Stefanie LaRue, who eradicated metastatic cancer from her body with the use of the oil. And thousands of others.

Wishing you all the best 2015, the best year yet,
Love
Karen

Re: HER-2 Positive & Triple Negative = Cannabis Intervention
 

Karen, I know someone who takes it for control of a brain tumor. Mentioned this to my onc this past Thurs and asked @ it as it is now sold in health stores in Michigan...he looked upset and told me not to take it. I am not on any chemo at this time. ????

Re: HER-2 Positive & Triple Negative = Cannabis Intervention
 

I may have posted this abstract once before ... We all know how long a clinical trial runs ...

Curr Med Chem. 2014 Jun;21(17):1923-30.
Is the clinical use of cannabis by oncology patients advisable?
Bar-Sela G, Avisar A, Batash R, Schaffer M1.
Author information
Abstract
The use of the cannabis plant for various medical indications by cancer patients has been rising significantly in the past few years in several European countries, the US and Israel. The increase in use comes from public demand for the most part, and not due to a scientific basis. Cannabis chemistry is complex, and the isolation and extraction of the active ingredient remain difficult. The active agent in cannabis is unique among psychoactive plant materials, as it contains no nitrogen and, thus, is not an alkaloid. Alongside inconclusive evidence of increased risks of lung and head and neck cancers from prolonged smoking of the plant produce, laboratory evidence of the anti-cancer effects of plant components exists, but with no clinical research in this direction. The beneficial effects of treatment with the plant, or treatment with medicine produced from its components, are related to symptoms of the disease: pain, nausea and vomiting, loss of appetite and weight loss. The clinical evidence of the efficacy of cannabis for these indications is only partial. However, recent scientific data from studies with THC and cannabidiol combinations report the first clinical indication ofcancer-related pain relief. The difficulties of performing research into products that are not medicinal, such as cannabis, have not allowed a true study of the cannabis plant extract although, from the public point of view, such studies are greatly desirable.

Re: HER-2 Positive & Triple Negative = Cannabis Intervention
 

There are 2 elements in cannibis (maybe more!) one, THC is what makes people stoned and the other is cannabidiol, (I think this is it) and this is what medical people are looking at positively regarding cancer. Obviously most cancer patients don't want to get stoned (ok for pain but not i you're working!) and so they have to separate the helpful element out of it. I read a little about it somewhere but can't remember but it sounded encouraging. We know it's helped people with glaucoma.

Re: HER-2 Positive & Triple Negative = Cannabis Intervention
 

Hi, Sarah,
Actually, the higher the THC, the better. I first thought the CBD was most important but it is actually the other way around.
Will start taking it as soon as I can get exactly what I need--
Yours,
Karen

Re: HER-2 Positive & Triple Negative = Cannabis Intervention
 

ok, well that's interesting! Guess we'll get fat but be happy! Good luck, keep us posted.
be well
sarah

Re: HER-2 Positive & Triple Negative = Cannabis Intervention
 

XOXOXO
Fat? Never, as long as there's yoga and discipline!
How are you all doing there in France?
Karen

Re: HER-2 Positive & Triple Negative = Cannabis Intervention
 

Unfortunately as a nurse I often get drug tested as well as in the state of California even though I can get a marijuana card , I would lose my nursing license if I got a card .
And I'm a non smoker ( virgin lungs here) but I do love brownies lol.
Now of course if you told me this could save my life I might just have to retire at the ripe age of 46

Re: HER-2 Positive & Triple Negative = Cannabis Intervention
 

I'm incredibly lucky to live in Washington state for our amazing oncologist and reaearchers, as well as legal cannabis. I have my medical card and basically everything you can think of for THC or CBD treatment, I can get at a reasonable price. I have CBD pills and a oil, as well as edibles that are made in professional kitchens. I can't tell you if they are shrinking my tumor... I'm sure it's the herceptin, but it does help with appetite and to relax. I talked to my oncologist about it and she said she can't tell me if it works or not to treat the growth, but she said I'm welcome to use it however I want.

I wish you all had it available to you!

Re: HER-2 Positive & Triple Negative = Cannabis Intervention
 

It's all very interesting and I think we'll see a progression of using cannabis more in the future.
For Nurse4u2day: had to smile at your comments. BTW: My dx was Stage IIIC , er/pr neg, Her2 positive also and am a nurse as well. Dxed 10 years this May, NED since that time

Re: HER-2 Positive & Triple Negative = Cannabis Intervention
 

Hello KDR and all,

I have been off the site for awhile. I too am very interested in the use of cannabis to treat and cure cancer.

I have read some articles and watched a few you tubes.
KDR-you mentioned an article I did not see a link?
Has anyone heard of Cannabis International?

What has me jump back on the site is after 6 years, I found a lump-pea type in my right-side (different side from cancer) scar line about 10 days ago-ultrasound indicates solid not fluid filled and I am having a biopsy this Wednesday.

Hugs!!

Re: HER-2 Positive & Triple Negative = Cannabis Intervention
 

Cal-Gal,
I didn't make note of that article, sorry. There are so many available.
Hoping for the bet for you,
Karen

Re: HER-2 Positive & Triple Negative = Cannabis Intervention
 

Thanks Karen!

Re: HER-2 Positive & Triple Negative = Cannabis Intervention
 

Too bad its the THC that is the active ingredient. Only because I did use pot during my last round of chemo and it was truly a godsend. I live in CA where its legal for medicinal purposes but also have the restrictions job-wise that it's still a federal offense. When I was going through chemo I could give a rip if it became a legal issue. 35 lb weight loss and I wasn't heavy to begin with and very, very sick in the end. But the feeling stoned was an issue. No way I could work using it regularly. I took a puff at night so I could eat. My experience is that it would be hard to still work. I've taken THC via pill and still had that stoned feeling. If they could find a way to deliver it and still be productive, all for it.

Re: HER-2 Positive & Triple Negative = Cannabis Intervention
 

Found the article I read before posting:
http://www.truthonpot.com/2013/03/09...ancer-therapy/


All the best, to all, always,
Karen

Re: HER-2 Positive & Triple Negative = Cannabis Intervention
 

Hi Amazing Group,

I found this topic interesting, didn't expect to take it too seriously and then I found this:
http://www.cancer.gov/cancertopics/p.../page4#_26_toc

Wow! This is totally legitimate and looks so efficacious, why isn't there more out there about it?????

Donna

Re: HER-2 Positive & Triple Negative = Cannabis Intervention
 

Hi Karen,
France is still great. Look me up if you ever get near the Cannes area.
Glad to see people are taking it in pill form not smoking it. smoking would always effect the lungs negatively. Good then that the US is legalizing it.
Julie, I haven't been taking pot but I can tell you, I couldn't have worked during chemo! I was flat on my back and consequently gained 15lbs! Taxol, Herceptin for 6 months, once a week and the anti-allergy drug they gave me made me stoned! The US is fairly puritanical so I would doubt there is any "high" in the medical version!
Be well all of you
A+ as they say here
sarah

Re: HER-2 Positive & Triple Negative = Cannabis Intervention
 

This is an area my sister and I are excited about! From what we've understood, it's important for the oil (you have to eat the oil not smoke it) to have near equal amounts of THC and CBD.

There's a phase 2 trial about to start in Israel testing the effects of cannabinoids on cancer in humans: https://clinicaltrials.gov/ct2/show/...&sel_rss=mod14

Here’s all of the other research I know about.

Breast-cancer specific:

August 2011 research from Dr. Sean McAllister on cannabidiol (CBD) inhibiting the spread of breast cancer.
http://www.medscape.com/medline/abstract/20859676
(More on McAllister and his research here.)

A 2010 study on cannabinoids specifically targeting her2
http://www.molecular-cancer.com/content/9/1/196#B4

A February 2006 study found anandamide (a cannabinoid neurotransmitter) inhibited the spread of breast cancer cells.
http://www.ncbi.nlm.nih.gov/pubmed/16343481

A 2011 study on the effect of cannabinoid on chemokine receptor CXCR4: http://www.ncbi.nlm.nih.gov/pubmed/2...?dopt=Abstract

2007 research by McAllister and Desprez -Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cell
http://www.ncbi.nlm.nih.gov/pubmed/18025276


Specific to other cancers:

1974 University of Virginia study found that tetrahydrocannabinol (THC) slowed Lewis lung adenocarcinoma and leukemia growth in a dose-dependent relationship: http://www.ncbi.nlm.nih.gov/pubmed?c...t_uids=1159836

1998 study from Dr. Manuel Guzmán showed THC induced apoptosis in glioma cells: http://www.ncbi.nlm.nih.gov/pubmed/9771884

A 2006 study by Dr. Manuel Guzmán found that THC could induce apoptosis in multiple pancreatic cancer cell lines: http://cancerres.aacrjournals.org/co...6/13/6748.full

A 2007 Harvard Study demonstrated THC inhibited multiple non-small cell lung cancer lines and reduced tumor weight and volume in mice by 50%.
http://www.ncbi.nlm.nih.gov/pubmed/21097714

A 2003 study showed activation of cannabinoid receptors induced skin cancer cell death: http://www.jci.org/articles/view/16116

1999 study in FEBS Letters found THC induced apoptosis in the PC3 line of prostate cancer: http://www.ncbi.nlm.nih.gov/pubmed/10570948

A 2011 study of the effects of THC on apoptosis in prostrate cancer.
http://www.ncbi.nlm.nih.gov/pubmed/22110202

June 2003 study demonstrated anandamide (a cannabinoid neurotransmitter) induced apoptosis in multiple prostate cancer cell lines.
http://www.ncbi.nlm.nih.gov/pubmed/12746841

October 2013 research at the University of London, St. Georges, showed that cannabinoids could kill leukemia cells.
http://ar.iiarjournals.org/content/3...ract#corresp-1

November 2013 study published in Case Reports in Oncology offers proof that cannabis extracts may be able to kill cancer in a human body.
http://www.karger.com/Article/FullText/356446

A November 2006 study found that liver cancer patients with higher expressions of CB1 and CB2 cannabinoid receptors had much better disease-free survival than patients with lower expressions.
http://www.ncbi.nlm.nih.gov/pubmed/17074588

November 2014 study showing that cannabinoids CBD and THC could shrink aggressive brain cancer.
http://mct.aacrjournals.org/content/...-0402.abstract

Re: HER-2 Positive & Triple Negative = Cannabis Intervention
 

Rosalie,
Thank you for sharing your research. Israel, Spain, why not US?

Karen

Re: HER-2 Positive & Triple Negative = Cannabis Intervention
 

I have smoked pot but it makes me paranoid, so I don't really like it. BUT if it would
Cure me or make my body feel better I would smoke it, eat it, or drink it. ��. I wish I knew more.