Anyone switch from Arimidex to tamoxifen?
I just about cant stand another minute on Arimidex!
The knee pain is horrible. I feel like I'm 100 years old. I have pain in my lower back too, but the knees are the worst. Moving helps and hurts...I have pain just laying in bed. After a year of trying to adjust, my onc switched me to tamoxifen. I haven't started taking it yet. I'm taking a week or two off to see how I feel without it. Anyone have experience switching with positive (or negative) results? Thanks |
Re: Anyone switch from Arimidex to tamoxifen?
Dee,
I don't have experience with tamoxifen but someone else on the board had once noted that they take their pill at bed time and they've had no issues on it. Sorry I can't offer more input but hopefully others will jump in and give their take on the matter. Good luck! |
Re: Anyone switch from Arimidex to tamoxifen?
Dee, I have not made that switch but I do have some experience with SEs from Arimidex. It was darn near crippling the first time I took it. I went off it for a month and restarted it and things were much better but ultimately, I discontinued it because I am not ER+ (I have a wacky HR status) and they aren't sure it will benefit my PR+ status.
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Re: Anyone switch from Arimidex to tamoxifen?
Hi Dee,
Why wouldn't your Onc put you on another AI like letrozole or aromasin? I was on tamoxifen for 4.5 years and hated every second. I was on letrozole for 5 years the first time and 4 years this time so far. Much better for me than tamoxifen, but everyone is different. Janis |
Re: Anyone switch from Arimidex to tamoxifen?
Dee
Trying a different Aromatase Inhibitor is an option. If the oncologist decides on Tamoxifen you have to be aware that Tamoxifen is an inactive prodrug. It becomes an active drug, Nor-Tamoxifen in your body using an enzyme called Cyp-2D6. Drugs that inhibit this enzyme prevent the formation of this active form. There are a lot of these drugs but many of the anti-depressants ie Prozac (Fluoxetine) Paxil (Paroxetine), and Wellbutrin (Bupropion) do this. So does Quinidine but Quinidine is a heart drug and I doubt you would be taking this. Paul |
Re: Anyone switch from Arimidex to tamoxifen?
I was on Arimidex for 8 years. Had to stop because of complicated bone issues. Onc put me on Tamoxifen and I had no discernable side effects at all.
Give it a shot! |
Re: Anyone switch from Arimidex to tamoxifen?
I had started on Arminidex and had to make a switch. The headache pain was severe. Onc then had me try another AI which was Femara which worked find.
Wishing you best of luck with new treatment. jean |
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