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-   -   Two New Genes. (https://her2support.org/vbulletin/showthread.php?t=62828)

Jean 03-16-2015 07:05 PM

Two New Genes.
 
http://www.medicalnewstoday.com/articles/288971.php

rhondalea 03-16-2015 10:20 PM

Re: Two New Genes.
 
23andMe tests rs10816625 but apparently not rs13294895, at least based on my results.

SNPedia has an entry for rs13294895, so one of the dtc companies is testing it.

23andMe has a nasty habit of assigning its own internal IDs to some SNPs instead of giving them RSIDs, so you have to look them up by their location on the chromosome. I tried that too, but the SNP still didn't turn up. (It has become even harder to translate the "i" SNPs now that everyone but 23andMe is using an updated assembly.)

I'm homozygous normal for rs10816625, and I wouldn't be surprised if I were normal for the missing SNP. So far, I've been normal for nearly all the SNPs implicated in breast cancer, except for a couple minor ones for which I'm heterozygous.

rhondalea 03-16-2015 10:34 PM

Re: Two New Genes.
 
Well, I tried Interpretome. Apparently rs13294895 is in high linkage disequilibrium with rs7875633, which is tested by 23andMe. Interpretome imputes that I am homozygous normal for this one too.

For anyone with a 23andMe account (or other account that provides raw data with RSIDs), you can go to Interpretome, click "Begin Exploring," upload your raw data file, and the click the "Lookup" tab. Just paste in the RSID, and if your SNP is in high LD with a SNP for which 23andMe tests, it will return the imputed result for the missing SNP.

Just like magic.


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