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Hopeful 05-17-2007 06:28 AM

Meta Analysis of Ki-67
 
http://www.breastcancersource.com/br..._27059___.aspx

Hopeful

Jean 06-03-2007 08:40 PM

Hopful,

Very interesting article, when I saw Dr. Slamon last April we discussed Ki-67 levels and he told then that this was a very important aspect of the tumor
and that the level and the fact of having a postive Ki-67 was extremely important and that my dr. in New York had missed the boat in not addressing
this aspect of my tumor.

Interesting, thanks for posting this article.

Jean

R.B. 06-04-2007 03:12 AM

Less omega six + more omega three = less Ki-67



RB


http://www.leaonline.com/doi/abs/10....journalCode=nc

Tumor prostaglandin E2 concentrations were reduced by feeding the lower LA level; further dose-dependent decreases occurred in the DHA dietary groups and were accompanied by reduced levels of 12- and 15-hydroxyeicosatetraenoic acids. These changes in eicosanoid biosynthesis may have been responsible for the observed decreases in cell proliferation, indicated by suppressed Ki-67 expression, and increases in apoptotic activity, as reflected in TdT-mediated dUTP nick end labeling immunohistochemical staining.


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