T-DM1 data at San Antonio
 

Wondered if there is going to be any update information about the efficacy of T-DM1 at the conference. I know it's early days yet but it seems so promising

Thanks
Ellie

Re: T-DM1 data at ASCO
 

Ellie,

At SABCS on 12-12-09 Genentech has a poster presentation(#5090) that displays results obtained from the phaseII T-DM1 trial that was fully enrolled (~100 participants) last February.
5090
A Phase II Study of Trastuzumab-DM1 (T-DM1), a Novel HER2 Antibody-Drug Conjugate, in Patients Previously Treated with Lapatinib, Trastuzumab, and Chemotherapy
Krop I, LoRusso P, Miller KD, Modi S, Yardley D, Rodriguez G, Agresta S, Zheng M, Amler L, Rugo H. Dana Farber Cancer Institute, Boston, MA; Karmanos Cancer Institute, Detroit, MI; Indiana University Melvin-Bren Simon, Indianapolis, IN; Memorial Sloan-Kettering Cancer Center, New York, NY; Sarah Cannon Research Institute, Nashville, TN; South Texas Oncology/Hematology, San Antonio, TX; Genentech, South San Francisco, CA; UCSF Comprehensive Cancer Center, San Francisco, CA.

Re: T-DM1 data at ASCO
 

That's the study I was on...I'm looking forward to finding out how I'm doing!

Re: T-DM1 data at San Antonio
 

Thanks for your replies. I understand that there are many T-DM1 trials looking at outcomes when used after different lines of prior chemo.
What is most encouraging is that we actually have trials in Britain!
Ellie

Re: T-DM1 data at San Antonio
 

Ellie,
It might interest you to listen in on Dec 14 when Roche will conduct a webcast to discuss new clinical data and results that they presented at SABCS.
http://www.roche.com/investors/ir_up...009-11-18c.htm

Re: T-DM1 data at San Antonio
 

roche will be talking about their data from chrisy's trial. and very likely could announce that they will be filing for 3rd line approval very soon, hoping for approval by mid late summer of 2010

run

Re: T-DM1 data at San Antonio
 

Thanks everyone for the information
Ellie