New proposed standards for IHC/FISH tests.Low volume labs not as good as high volume
The first article sets new recommanded threshold levels for IHC & FISH tests for HER positivity.
The second article shows discrepancies in lab results accuracy depending on the volume of performed tests with the local labs showing the lower accuracy http://www.ncbi.nlm.nih.gov/entrez/q...=pubmed_docsum HER2 Testing in Breast Cancer: NCCN Task Force Report and Recommendations. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=Abstract&li st_uids=16809727&query_hl=1&itool=pubmed_docsum HER2 testing by local, central, and reference laboratories in specimens from the North Central Cancer Treatment Group N9831 intergroup adjuvant trial. |
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