Determination of HER2 amplification - when should chromosome 17 also be determined
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Is it just me or does it seem equivocal FISH and this polysomy 17 issue is being bounced around with no clear recommendations?
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They probably need to understand the ramifications of this and possible studies to support what they might be looking for.
I am just commenting that Chromosome 17 is the chromosome BRCA 1 resides. There may be a familial link for those who are Her2+ and have polysomy 17 perhaps? (Just thinking out loud here). PS - BRCA 2 resides on Chromosome 13 |
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