T-Dm1: "'...decreased in size... density"
 

My wife started T-DM1 about two months ago, her CT scan came back yesterday, and it's been many years since I read the phrase "...decreased in size ..."

Many thanks for all the good thoughts,

Nguyen



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Linda's treatment history:

07/2014 - current: T-DM1
02/2014 – 06/2014: Everolimus (5mg), Exemestane, herceptin
08/2013 – 01/2014: Femara, herceptin
12/2012 – 07/2013: 4mg estradiol, herceptin
08/2012 - 12/2012: Fulvestran 500mg, exemestane, Herceptin (Stop everolimus due to mouthsores)
05/2012 - 08/2012: Everolimus (10mg), Exemestane, Herceptin, Zometa
08/2011 - 05/2012: Herceptin, Tykerb, Femara, Zometa
08/2010 - 08/2011: Herceptin, Femara, Zometa
09-2009 - 08/2010: Herceptin and estradiol (6mg)
09/2008 - 09/2009: Herceptin, Fulvestrant, Femara
03/2008 - 09/2008: Herceptin, Exemestane, Oophorectomy
01/2005 - 03/2008: Herceptin (readded) and Femara
07/2004: It returned again via several small nodules in the lung
10/2002: NED (via CT and CA27.29)!
10/2001 - 01/2005: Femara, (Fosamax)
12/2000 - 10/2001: Herceptin and Navelbine
12/2000: lung metastatic was diagnosed (a few small nodules)
02/1998 - 12/2000: Daily Tamoxifen
05/1997 - 04/1998: Modified Radical Mastectomy, many many cycles of chemo regiments (CAF,Taxol, Carpoplatin, Thiotepa, Navelbine, Taxotere), including HDC, and radiation
05/1997: First diagnosed with BC stage 3A, ER+, PR+, HER2 +, poorly differentiated, nuclear grade 3.

Re: T-Dm1: "'...decreased in size... density"
 

Awesome news

Re: T-Dm1: "'...decreased in size... density"
 

That is wonderful news. So happy to hear the cancer is shrinking.

Re: T-Dm1: "'...decreased in size... density"
 

Great news Nguyen! So glad for you both.

Re: T-Dm1: "'...decreased in size... density"
 

That is wonderful! Thanks for sharing the good news.

Re: T-Dm1: "'...decreased in size... density"
 

Great News! May it Continue! Cathy

Re: T-Dm1: "'...decreased in size... density"
 

I am so happy to read your news!
May T-DM1 be the charm forever,
Karen

Re: T-Dm1: "'...decreased in size... density"
 

Thanks for sharing this good news, it is always such a morale boost!

Carol Ann

Re: T-Dm1: "'...decreased in size... density"
 

that is great news - a quick response is agood indicator of continued good response. my wife is asuper responder to tdm-1, ned almost 3 yrs. heres' praying your wife gets to ned too ! talk with your dr. about anti -estrogen tx. , to help prevent any re-occ. ahve your doc consult w/ Genentech on latest tx for those who are er+, and her2 +. my wife is her2 only. our doc has talked about possibly treating er+her2 + with t dm-1 to hopefully get to ned then trying just herceptin and tamoxifen for maintenance /reocc. prevention . God Bless and continue to Heal !

Re: T-Dm1: "'...decreased in size... density"
 

Dear Nguyen,

So glad to hear such great news. Yeah!

Hugs and blessings to you and your family.

Re: T-Dm1: "'...decreased in size... density"
 

Thank you for sharing! I'm glad she's responding well to TDM-1.

I'm also impressed she's had lung mets for almost 14 years and has (apparently) been pretty stable. If I make it 14+ years I'll be in my 70s--not exactly a "normal lifespan" for my family (lots of centenarians or close to it), but a pretty decent run.

Congratulate her on being a poster child for "cancer as a chronic illness." I hope she's having a good, happy life.