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News 01-21-2010 11:51 PM

AKD Global announces new class of cancer treatments in development
 
AKD Global announced today the discovery of a new class of cancer treatments in development, providing hope for millions of sufferers. The spectacular results demonstrate a highly potent effect on cancer cells with no toxicity to healthy tissue. AKD is raising funds to continue development.

More...

Rich66 01-22-2010 09:31 PM

Re: AKD Global announces new class of cancer treatments in development
 
Ha! Another incredibly secret cure is on the way.
Rudimentary website here:
http://akdglobal.com/3.html

Ellie F 01-23-2010 05:01 AM

Re: AKD Global announces new class of cancer treatments in development
 
The plot thickens!!!
Is this just another miracle treatment that only works in mice??
Ellie

Unregistered 02-05-2010 07:08 AM

Re: AKD Global announces new class of cancer treatments in development
 
No, Ellie. This is real. Apoptotic induction is reproducibly observed in cancer cells after exposure to these molecules. Outstanding results have demonstrated zero toxicity to healthy tissue.

Dennis 02-07-2010 06:42 AM

Re: AKD Global announces new class of cancer treatments in development
 
1.) Mechanism of action:

The proposed mechanism of action is consistent with activation of apoptotic pathways in cancer cells - as evidenced by exponential increases in caspase 3 protein - after exposure (16hr) to our antineoplastic.

2.) Why is it differentiated?:

Our molecule is a novel alpha amino acid, selective and presumed to target rapidly proliferating cells (cancer). In contrast to chemotherapy and radiation therapy - both which are non-selective.



3.) How did we test the cancer cells in-vitro and in mice?:

In-vitro testing was performed with U-87 (human astrocytoma), HEP G2 (liver cancer) cell lines. Cell viability testing demonstrates the antineoplastic activity. We used 50,000 cells/well - MEM supplements- incubated at 37*C. Reproducible dose response curves show a greater than 90% inhibition - with MEM supplemented plates - using our compound.

Oral maximum tolerated dose (MTD) testing performed with mice indicate no evidence of toxicity at all levels tested (thousands of times higher than the levels used in our in-vitro testing. This is highly suggestive that our compound has no toxicity to healthy tissue.

4.) Can the mouse model be reproduced?

Absolutely. We welcome independent verification of all claims.

5.) Can we make any forward looking statements about the mouse model to humans?:

Absolutely. Mice are used for toxicology testing - they have very similar DNA to humans.

6.) What potential indications?

Originally, potential indications were for therapeutic compassionate usage in late stage and terminal cancers. Our antineoplastic may find usage with early treatment of breast cancer, prostate cancer, as well as blastomas, carcinomas, lymphomas, sarcomas.

www.akdglobal.com

http://www.businesswire.com/portal/s...07&newsLang=en


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