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eric 08-10-2008 06:53 PM

trial of resveratrol closer
 
Coming soon, a `wine` drug that fights ageing, diabetes and cancer
http://www.zeenews.com/articles.asp?...id=env&ssid=28

London, Aug 10: A drug, which holds back the clock of ageing and halts the onset of diabetes, cancer and heart disease, may hit market shelves in another five years, researchers have claimed.

According to the scientists, the magical drug can be used to prevent Alzheimer's and can also reinvigorate patients giving them more stamina.

The drug is made up of chemicals that mimic resveratrol, a compound which is found in the skins of red grapes.

Earlier studies have shown that resveratrol cuts the impact of a high-fat diet, doubles stamina and extends lifespan in mice.

However, to get the same benefits, a human would have to drink around 1,000 bottles of wine.

Now, Sirtris, a pharmaceutical firm has developed a pill based on two chemicals that act in the same way.

In one study on mice, which was published last year, the drug was found to undo diabetes' symptoms.

The first clinical trials on humans are now under way, and the developers - Sirtris Pharmaceuticals - believe it could also help prevent diseases including cancer, heart disease and Alzheimer's.

"The excitement here is that we're not talking about red wine any more. We're talking about real drugs. We will make a drug to treat one disease but it will, as an added bonus, protect you against most of the other diseases of the Western world. One of the drawbacks of resveratrol is that the doses need to be large," The Daily Mail quoted David Sinclair, co-founder of Sirtris, as saying.

"Now this paper says you can reduce it into a little pill taken once a day. The chances of success in humans is estimated at 80 to 90 percent," he added.

David's researchers have tested around 500,000 molecules to find those that would have the same effect as resveratrol on genes known to control the ageing process.

The same results were seen in two studies, which were conducted on mice and one of rats.

Another study, which was conducted last month, showed that mice fed resveratrol had strong bones, healthier hearts, better balance and co-ordination, and fewer cataracts than those not given the compound. It also helped them live longer if they had a high-calorie diet.

Rich66 10-22-2008 02:01 AM

I see resveratrol on the shelves at Walgreens. Probably not a very strong dose, eh?

fullofbeans 12-11-2008 06:14 PM

Rev mimic the same chemical that is produced by your body when you are fasting..

Remember that in an another post and a recent study showed that in fasting mice (after 2 days fast) chemotherapy hardly affected their normal cells but only their cancer cells..and that somewhat the process of fasting protected them from the harsh treatment..

put 2 and 2 together..

feonad 03-09-2011 11:10 AM

Re: trial of resveratrol closer
 
my friends doctor at sloan kettering said to take the over the counter supplement since he said cancer can't live with that supplement.

chrisy 03-09-2011 11:48 AM

Re: trial of resveratrol closer
 
1000 bottles of wine, that's a lot of wine. think of how much chocolate you'd need to adquately pair it.

But, I've been following news on resveratrol for some years and would be interested to see what the equivalent dose actually is!

kiwigirl 03-09-2011 12:18 PM

Re: trial of resveratrol closer
 
I used this during my radiations i heard you can not used during chemo but as an every day maintenance after chemo is good. And aids is radiation to work.


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