Determination of HER2 amplification - when should chromosome 17 also be determined
 

http://www.abstracts2view.com/sabcs/...u=SABCS08L_237

Hopeful

Is it just me or does it seem equivocal FISH and this polysomy 17 issue is being bounced around with no clear recommendations?

They probably need to understand the ramifications of this and possible studies to support what they might be looking for.

I am just commenting that Chromosome 17 is the chromosome BRCA 1 resides. There may be a familial link for those who are Her2+ and have polysomy 17 perhaps? (Just thinking out loud here).

PS - BRCA 2 resides on Chromosome 13