Fever with Herceptin?
 

I restarted a 2nd round of Herceptin (Tykerb and Xeloda in between). I had the 2nd dose last week on Thursday and have been running a fever with flu like symptoms ever since. Has anyone else had the side effect of fever (Up to 102.5) on Herceptin? I have been taking Tylenol but the fever is being very persistent.

The first time I did Herceptin I had no side effects at all.

I had a fever and flu like symptoms the first few doses of Herceptin DM1. Not quite as high, but I usually run very cool (in the 97's) so for me a fever of 101 was high. Granted, this was not "pure" herceptin, but when I called the doctor, she responded that since the herceptin is an antibody, it's not unusual to have a fever. She felt it was due to the "herceptin" piece, not the DM1. Mine responded well to ibuprofen but it did hang on a few days.

I also didn't remember having this the first time on herceptin, but then I got it with chemo so I might not have been thinking clearly!