anyone on this ?-New Peptide-Based Vaccine Trial opened with the Tumor Vaccine Group
 

Anyone have enrolled this trial? or the first one?
could give me some opinion or information about their HER-2/neu (HER2) intracellular domain (ICD) peptide-based vaccine ?
Anyone tried this ?
thank you !



The Tumor Vaccine Group at the University of Washington is a multidisciplinary group of investigators focused on the diagnosis, prevention and treatment of cancer with novel, immune-based therapies. Involving scientists, doctors, nurses, and patients, our translational research works to bring the most innovative treatments from the bench to the bedside and to harmonize scientific study with patient care.

We invite you to explore the work we are doing, through scientific research and clinical trials, to further cancer’s diagnosis, treatment, and prevention. This site provides an introduction to immune therapies and our ongoing clinical trials program and pre-clinical research projects.
http://depts.washington.edu/tumorvac/trials.php

DonaldDonald,

I am currently enrolled in the trial. I have had 2 vaccines that consisted of 3 shots each vaccine. I will get another vaccine at the end of the month.

You can find trial requirements by going to the University of Washington web site.

Amelia

Hi I have been looking at her2 vaccine trials on the American clinical trials database and also here in England but am getting totally confused.Does anyone know if all the trials are looking at the efficacy of the same vaccine or are there in fact several different types of peptide vaccines?Grateful for any information Ellie

Amelia,

It is so glad to hear from you!
I am now on contact with the group for my wife, and we need more opinions to make a decsion.
By the way, as we live in Macao, it is so far to go to Seattle to have that vaccine trial. It is a hard decsion for us!
What is the most important information of the vaccine to make your selection?
thanks for sharing and wish you good health!
Keep it up! we all need this!

Ellie,
As I checked the internet, there should be different groups working at different vaccines! they might have the same idea or model, but anyway there is a little bit different some how.

Thanks Donald, thought about the Washinton trial at Seattle but also a long way from England! Not sure even if they would consider me as a non US citizen. Ellie

internationaly patient
 

They said they welcome international patients as well, but for us, the medical insurance would be a real problem, cause we are "insurance free" there.
The medical fee is high there!
Let's look into that hand in hand! and keep in touch!
don't give up!
and, Amelia, We need your help to tell us more experience, please keep in touch also, thanks!
with good wishes!

Donald

DonaldDonald,

You do not need medical insurance to take the vaccine. You have to pay to get here and where you are going to stay.

Your doctor at home could assist with the scans and other medical information.

Amelia

Thanks Donald and schoolteacher. I am due to see a new onc in a couple of weeks (after a lot of hassle to get a second opinion-it really feels sometimes that fighting the disease is only half the battle)and intend to take the vaccine info with me to see what he thinks and to get as much info from him as possible.Good to hear that we may be able to get into this trial as I don't have insurance but could cover travel costs etc.Ellie

Dear Amelia and Ellie,

It is lucky to have you two together to share with me!
I can manage our travel and lodging though it is so expensive for me, but friends keep telling me that the medical expense is so high in U.S. so if my wife should have any uncomfortable, it would be a financial disaster for us.
That hold me dare not to have any decision about the trial but just keeping contact with the gourp and wait to see.
And Also both my wife and me never travel to U.S. or England, going so far to settle down for a medical trial is really a challenge.
Besides, we have a 8-years old boy to take care too, that also is our consideration.
Lots of things for me to think over and over, that keep me can't sleep every night !
Let's see if I could conquer all and let my wife have a possible cure.
Thanks again! keep in touch!
Donald

Amelia,

Could you tell me more about the trial? May be in private Message?
How long you stay in Seattle every time?
Where to stay? How much it cost?
How do you feel after the vaccine?
How about the Leukapheresis?

Really thanks for your help, for I never been in U.S. that the trip would be an adventure for me.

Donald

Donald: Have you looked into the vaccine trials at John Hopkins in Baltimore, Maryland. I understand a new trial was slated for this spring and they have had several others. Dr. Leisha Emens heads the vaccine research and trials.

I hope this is helpful in some way.

Wishing and sending you my best...Darlene in Virginia Beach

Darlene: Thanks for concerning and the helpful information! I will check the trial out if it is suitable for my wife.
But most of the trial only accept patients in NO progressing situation, so it is hard to find a vaccine trial for my wife.
Thank you again and keep in touch! take care!
Donald

Donald: I noticed a previous post that indicated your wife was on Tykerb. I am not familar with her entire history, but how about the TDM1 trials?

Forgive me if I am bringing up info you already are aware of, just hoping something might be right for your wife.


Take care

Darlene

Dear Darlene:
As you know that my wife is having lapatinib, and the T-DM1 trial is not allow patients who Prior treatment with lapatinib or capecitabine. So my wife is on the excluded list.
I can only hope the T-DM1 could be on market A.S.A.P., so it could help lots of people!
And your help is welcome anytime!
by the way, what is a BRAIN METS MANAGEMENT PLAN? how could the plan help peoples?


Dondld

anyone on this ? - New Peptide - Based Vacine Trial opened with the Tumor Vaccine Gro
 

This made be way off center, but I am wondering if there is anything at the University of Washington website directing patients from other areas to low cost temporary housing in the area? There must be someone there who can advise patients about those things.

DONALD, HOW ABOUT THIS ONE, NCI AT UNC CHAPPELL HILL LINEBERGER CANCER CENTER IN NORTH CAROLINA.

Protocol No.
LCCC0418Principal InvestigatorSerody, JonathanPhasePhase IIScopeLocalSecondary Protocol No.5-R21-CA105837-01-02TitlePhase II Trial Evaluating the Toxicity and Efficacy of a Multiepitope Dendritic Cell Vaccine Given with Trastuzumab and Vinorelbine for the Treatment of Women with Metastatic Breast Cancer that Express HLA-A0201 and Whose Tumors Overexpress Her-2/NEUApplicable Disease SitesBreast - FemaleDrugs InvolvedDENDRITIC CELL VACCINE
HERCEPTIN
NAVELBINE
TRASTUZUMAB
VINORELBINEStatusOpenParticipating InstitutionsUNC-CHEligibility DocumentLCCC0418 Eligibility Criteria sig.pdf

Here is a link from the Seattle Cancer Care Alliance website regarding lodging and transportation.

http://www.seattlecca.org/scca-housi...sportation.cfm

Long term (2 weeks to a month+) housing starts at about $800.00 a month and goes up from there. They do have many options and many of the hotels offer special rates to those receiving cancer treatment. My secretary's daughter works at SCCA and I have a lifelong friend that works at Fred Hutchinson. I'm sure they must have special programs for people seeking treatment. Let me know if I can be of any help.

Thanks for all the warm hearts here!
My wife is now having Vinorelbine injection and Tykerb now, so it seems our plan to apply for Seattle Trial must be wait and see! and, actually I don't know which Trial would be the best suit for her.
As we have government medicine support here in Macao and no support in the U.S., so we will check very carefully before decision making, it must be something more promising.
How about the NeuVax? Is it almost done? Would it be on the market within one year? and Is there a trial open for patients?
Donald

We spoke with Genentech representatives at the AACR meeting in Denver.

They will be opening new trials shortly with more lenient criteria so your wife may qualify. Keep a lookout.

Joe

Thanks Joe!
by the way, could you tell me how to add those medical history information under the post?

Thanks again! Joe!
Let me try !

Re: anyone on this ?-New Peptide-Based Vaccine Trial opened with the Tumor Vaccine Gr
 

I am currently investigating joining this trial as well. Anyone else here in the trial? I'd be interested in reading about your experience. Amelia - how is it going? Anyone else? Thanks in advance for any useful information you can provide.

Re: anyone on this ?-New Peptide-Based Vaccine Trial opened with the Tumor Vaccine Gr
 

I finished the vaccine in June. So far, so good. I miss going to Seattle once a month.

Amelia

Re: anyone on this ?-New Peptide-Based Vaccine Trial opened with the Tumor Vaccine Gr
 

Hi, I fly to Seattle, from Tampa, FL - My last vaccine is in
November - Dr. Salazar is great. If this vaccine is not for
you, there are others, call interview them, I travel along way but, it fits for me.

I do get flight and hotel assistance.
Anyone that is on vaccination from Seattle, interested in talking with you private mess.

Re: anyone on this ? - New Peptide - Based Vacine Trial opened with the Tumor Vaccine
 

I go there once a month, the American Cancer Society can help with lodging.

Re: anyone on this ?-New Peptide-Based Vaccine Trial opened with the Tumor Vaccine Gr
 

I'm on it - last one is in Nov. for me - I travel from tampa, to seattle once a month. Ive been posting im on this vaccine - would like to hear from some people.
So far - I'm doing great.

8/08 DCIS
9/08 lump, clear lymph node
10/08 - liver met., chemo ts, carb herc
1/09 - ned
6/09 - vaccine
11/09 - last vaccine

1/09 to present ned
normal bloodwork/scans

Re: anyone on this ?-New Peptide-Based Vaccine Trial opened with the Tumor Vaccine Gr
 

They are having an open house - November 5, 5-9
in Seattle - the application, contact information is
at my website www.caringbridge.org/visit/margierose
I have about 2 links to the vaccine in Seattle with
Dr. Salazar.

Re: anyone on this ?-New Peptide-Based Vaccine Trial opened with the Tumor Vaccine Gr
 

Do you know if they are still recruiting patients for this trial?
Thanks,
Sandra

Re: anyone on this ?-New Peptide-Based Vaccine Trial opened with the Tumor Vaccine Gr
 

Sandra,

I am pretty sure they are still recruiting for the vaccine trial at the University of Washington.

Amelia

Re: anyone on this ?-New Peptide-Based Vaccine Trial opened with the Tumor Vaccine Gr
 

Thank you, Amelia.
Sandra

Re: anyone on this ?-New Peptide-Based Vaccine Trial opened with the Tumor Vaccine Gr
 

I am once again considering joining this trial. For those of you who have blazed the trail, any thoughts? How are you doing post-vaccine? Would you make the same decision to do the trial today? Any advice is appreciated. Thank you so much!

Re: anyone on this ?-New Peptide-Based Vaccine Trial opened with the Tumor Vaccine Gr
 

Courtney,

The people at the Tumor Vaccine Group at the University of Washington are a really great group to work with. I just did a blood draw on the 12th of this month. I have not gotten any results because my blood has not been analyzed yet. I don't know how many more people are needed to complete the trial.

Amelia

Re: anyone on this ?-New Peptide-Based Vaccine Trial opened with the Tumor Vaccine Gr
 

I was accepted into this trial and am heading to Seattle on Monday, May 3rd for my first vaccine treatment! Keep your fingers crossed!!!

Re: anyone on this ?-New Peptide-Based Vaccine Trial opened with the Tumor Vaccine Gr
 

Courtney,

I will be thinking about you on Monday. Please tell the staff I said, "Hello." They are a wonderful group of people.

Let me know how things go.

Thanks for participating.

Hope we are getting close to have the number of people needed to get the paper written.

Amelia

Re: anyone on this ?-New Peptide-Based Vaccine Trial opened with the Tumor Vaccine Gr
 

Hi, I finished the UW vaccine phase 3 last
May with follow-ups at my local onc every
3 months. I didn't have any problems
but I would recommend you clearly know
what amount the vaccines are for your
treatment at each time. They follow you
through you local onc for 1 year and 8
months from start. Being away from
my family and the flight cost was a strain
but virgin America is least expensive and
you can ask ACS for no cost hotels. The
trial is now in the next phase which says
it did the job and now they are going through
randomize. Very professional team and
I am happy I did it.

Re: anyone on this ?-New Peptide-Based Vaccine Trial opened with the Tumor Vaccine Gr
 

I am new to this message board, but I did all 7 visits to U of Washington , and finished this time last year. I am so glad that I did. I have been in remission since Dec. 24 a year and a half ago , and latest CT scan shows NED . If you qualify for the study ( via Contact with Nicole Bates ) , I would recommend it . Lynn