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RhondaH
11-19-2009, 08:56 AM
http://blog.dslrf.org/?p=116

hutchibk
11-19-2009, 12:45 PM
Wish I could be at SABCS to see the roast of her stance.

StephN
11-19-2009, 01:14 PM
Here is what looks to me like a "smoking gun." Once the shock has worn off, my memory cells started working. I heard Dr. Love talk about the "intraductal approach" to breast cancer at San Antonio in 2004. Then I received an oversized brochure announcing the 3rd or 4th Annual Breast Cancer Intraductal Approach Symposium. From one of her organizations.

Anyone who says she does not stand to benefit by a change in the way breast screenings and diagnostics are done, should take a look (emphasis is mine):

http://www.biomedcentral.com/graphics/flashes/openaccess-large.gif (http://www.biomedcentral.com/info/about/openaccess/)Meeting report
State of the Science and the Intraductal Approach for Breast Cancer: Proceedings Summary of The Sixth International Symposium on the Intraductal Approach To Breast Cancer Santa Monica, California, 19–21 February 2009

Susan Rochman1 http://www.biomedcentral.com/graphics/article/email.gif (http://www.biomedcentral.com/logon/logon.asp?msg=ce), Dixie Mills1 http://www.biomedcentral.com/graphics/article/email-ca.gif (http://www.biomedcentral.com/logon/logon.asp?msg=ce), Julian Kim2 http://www.biomedcentral.com/graphics/article/email.gif (http://www.biomedcentral.com/logon/logon.asp?msg=ce), Henry Kuerer3 http://www.biomedcentral.com/graphics/article/email.gif (http://www.biomedcentral.com/logon/logon.asp?msg=ce) and Susan Love1 http://www.biomedcentral.com/graphics/article/email.gif (http://www.biomedcentral.com/logon/logon.asp?msg=ce)
1Dr. Susan Love Research Foundation, Santa Monica, CA, USA
2Case School of Medicine and University Hospitals, Cleveland, OH, USA
3MD Anderson Cancer Center, Houston, TX, USA

BMC Proceedings 2009, 3(Suppl 5):I1doi:10.1186/1753-6561-3-S5-I1
Published:24 July 2009
Abstract

Researchers are using the intraductal approach to advance breast cancer risk assessment, prevention, diagnosis, and treatment. Procedures and technologies that can access and interrogate the ductal-alveolar systems include nipple aspiration, ductal lavage and ductoscopy. Ductoscopic papillectomy, ductoscopic margin evaluation, and intraductal therapy are considered promising investigational and innovative treatments. These techniques are used to explore the biology of the normal breast; collect and analyze breast fluid and cells to identify biomarkers that can be used in breast cancer detection and risk assessment; and to identify new ways to find and administer therapeutic and/or preventive agents to the breast tissue. This report summarizes the latest research findings in these areas, presented at The 6th International Symposium on the Intraductal Approach to Breast Cancer in 2009.

Maybe this will be a better way to work with breast issues, but IF it is so great and revolutionary, why is it taking so long to get approved and into mainstream use??

Perhaps by supporting the Preventative Task Force's latest guidelines, she is helping open the door to a rush in getting something she is involved in approved. Just speculating here, but I foresee SOMEONE riding into this gap with shining armor blinding the truth.

WolverineFan
11-19-2009, 08:42 PM
I'm not buying her position at all. I am not saying that there might not be something better out there for screening, but until something better is determined, why on earth would we look at eliminating one of the tools we have to assess breast health for women under 50. It is crazy to me, and I just see red everytime I hear or read of this!!!

hutchibk
11-19-2009, 10:59 PM
I seem to remember her last year talking about either this or another diagnostic tool/theory that she was in partnership with to start trials imminently in either China or Japan... and I seem to remember she had hopes that it would prove itself and be rushed into the market.

I would love to find the info. She was very excited about it and had high hopes if I remember correctly. I would like to see just how deeply involved she is in the technology.

Debbie L.
11-20-2009, 03:14 PM
I'm not even going to try talk about this, with the level of bias, anger, and fear that abounds here right now. But I WILL sign my name (laughing). I see that the few who have tried to inject some reason into these rants haven't signed their name - whether from simple oversight or fear of flaming we won't know. Anyway - here's one fairly simple, calm and unbiased editorial from the NYT, sent by me,
Debbie Laxague, who agrees with this editorial:

November 20, 2009
Editorial - The New York Times

The Controversy Over Mammograms

An expert panel's recommendation that mammography
screening to detect breast cancer be scaled back
has caused consternation among women and doctors
and prompted some attempts to connect the results
to the debate over health care.

It is important to keep the findings and
recommendations in perspective. They are guidance
for women and doctors. The decision about whether
to be screened is properly left to each woman –
to determine with the help of her doctor what
risks and benefits she is most comfortable accepting.

The new recommendation came from the United
States Preventive Services Task Force, a
government-appointed group of 16 outside experts
created 25 years ago to advise the Department of
Health and Human Services on the effectiveness of
various screening techniques. Half are women. The
panel‚s mission and expertise are medical, to
determine whether mammograms do more good than harm for women of various ages.

Its most controversial recommendations – in
conflict with recommendations from the American
Cancer Society and other medical groups – were
that women in their 40s should not routinely have
mammograms and that women between ages 50 and 74
should have mammograms every two years instead of
annually. That recommendation was based on an
analysis showing that every-other-year screenings
could provide 80 percent of the benefits of
annual screening while cutting the risks almost in half.

These recommendations have shocked many people,
but the American College of Physicians made
similar recommendations two years ago and the
National Breast Cancer Coalition, an advocacy
group for patients, has been saying for years
that mammography screening has been oversold, has
significant limitations and can cause harm. It
urges women to make their own decisions based on the best available facts.

In suggesting that women in their 40s not get
screened (unless they are at high risk for breast
cancer), the panel argued that the harms of
mammograms for those women appear to outweigh the benefits.

Screening turns up lots of tiny abnormalities
that are either not cancer or are slow-growing
cancers that would never progress to the point of
killing a woman and might not even become known
to her. If a suspicious abnormality is found,
women usually get another mammogram or imaging
test to better identify it and often a biopsy to
determine if it is cancerous. If it is, most
women have it treated with surgery, radiation,
hormone therapy or chemotherapy, all of which carry risks for the patient.

The scientific argument is that it is not worth
taking such risks for the large number of women
whose cancers grow too slowly to kill them. But
it is difficult, in practice, to apply that kind
of scientific analysis to the immediate questions
confronting a woman and her doctor when a
mammogram turns up an abnormality. The only real
solution will come when researchers find a way to
distinguish the dangerous, aggressive tumors that
need to be excised from the more languorous ones that do not.

The task force acknowledges that mammography
saves lives among women in their 40s. But it
estimates that more than 1,900 women have to be
screened for a decade to save a single life.
Among women in their 50s, when breast cancer is
more common, only about 1,300 women have to be
screened; among women in their 60s, only 377.

The panel concluded that the benefits outweighed
the risks among those over 50, but not in the
younger group. It found insufficient evidence to
determine whether digital mammography or magnetic
resonance imaging, two newer and more costly
technologies, are any better than standard film mammography.

The panel also cites the anxiety and distress
that many women experience when a mammogram finds something suspicious. Many women find that
argument condescending. Women in their 40s are
perfectly capable of managing anxiety and
deciding for themselves whether the uncertainty
that follows the detection of an abnormality in
their breast is worth enduring to know whether they have cancer or not.

Opponents of the health care reform bills moving
through Congress have seized on the new
recommendations as evidence that the government
is seeking to put bureaucrats between you and
your doctor or that it would ration care by
denying coverage for some mammograms that are now covered.

There is virtually no chance that any insurers,
either public or private, will deny coverage to
anyone based on these recommendations. Government
and industry officials have said that explicitly
and, in fact, every state but Utah requires
private insurers to pay for mammograms for women starting in their 40s.

There is nothing in the reform bills that would
change the current Medicare laws, which require
that annual mammograms be included among the
preventive services covered, an important benefit
for more than a million women in their 40s who
get Medicare coverage because they are disabled
or suffering from end-stage kidney disease.

The only part of the reform bills that could
affect mammography would only make them more
accessible. Under the legislation, the secretary
of health and human services might be given
authority to waive Medicare co-payments for
prevention services that rank highly in the
opinion of this task force. Since the task force
gave a low grade to screening women in their 40s,
the secretary could not waive cost-sharing for them.

There is nothing wrong with a healthy public
debate about mammography within the medical
community and among women who must decide when
and how often to get screened. It should not be
injected into the partisan debate over health care reform.

margiermc
11-20-2009, 03:37 PM
She was paid off - by the Task Force Panel.

I'm proud that I never bought any of her books, never
listened to her - realized she was just a researcher and
not a breast cancer survivor, nor any kind of specialist
in breast care - just, a dr., researcher and writer -
making money, but, wake up, she is not on our side!

I will fight tooth and nail - and - I don't care who i
tell - this is going to be a disaster -

your new health care will be passing on Saturday by
the senate

they are coming out with all kinds of new guidelines, the insurance co. are already gearing up, for new cuts,
and you have someone who was suppose to be on the side of breast cancer survivor's , Dr. Love - all she did was sell books.

margie

Laurel
11-20-2009, 03:58 PM
Hmmm, I just do not know, Debbie. I was a faithful mammogram gal since age 40. At age 48 they saw a clustering of calcs and performed a bx. It was positive for BC. Subsequent surgery and testing indicated a small invasive tumor, 7mm, no vascular invasion, BUT it was Her-2. If this had not been found until I was age 50 would I be stage I? See, I think it is worth the expense to be screened annually. My annual mammogram singularly has gifted me with an early stage, early detected, aggressive tumor. Should I never recur I chalk it up to that mamo and Herceptin.

I feel like the proverbial lobster in the pot of water, swimming away as the temperature rises. I'm just not lulled into lockstep on this one. Sorry. I think this is a bad go and will be proven so in years to come. I am a conscientious objector.....

StephN
11-20-2009, 04:28 PM
Have I got this right?
"Cost-sharing" when the mobile mammography vans go around to poorer and underserved parts of cities and rural America attempting to reach higher risk parts of our population?

Will these screenings still be free, or even available?

I have so many questions. How will I be able to give support with a clear conscience if I do not stand up for the right of everyone to have some way to assess their breast health at a time when they are vulnerable? (Knowing what I do know about this fickle nature of breast cancer and the difficulty in proving who is high risk and who is not.)

Rich66
11-20-2009, 04:39 PM
Screening turns up lots of tiny abnormalities that are either not cancer or are slow-growing cancers that would never progress to the point of killing a woman and might not even become known to her. If a suspicious abnormality is found,
women usually get another mammogram or imaging test to better identify it and often a biopsy to determine if it is cancerous. If it is, most women have it treated with surgery, radiation, hormone therapy or chemotherapy, all of which carry risks for the patient.

The scientific argument is that it is not worth taking such risks for the large number of women whose cancers grow too slowly to kill them


Well..that scenario, process and "science" would apply to all screening at any age. But..if a slow growing tumor is found in a young woman, it could be argued it has a greater chance of killing her since it has a greater head start. In fact, it is pretty well established that BC in younger patients tends to be the more aggressive types. More aggressive cancer, undetected..over a longer period of time. Hmmm.
I remember hearing this thinking about older women years ago. Now it's being played out at the other end of the age bracket.

That's a logical (I think) way to look at it. And it also fits with people's intuition and years of PSAs. Makes it a hard sell from both angles.

And yeah..mammography is oversold in the sense that it also has significant false negatives. I wonder how many women have taken false assurance from a negative mammo and stopped any self-exam. I forgot..those are unnecessary.

But..I'm glad it won't get run up the beancounter's flagpole. Might keep an eye on it anyway.

Margerie
11-20-2009, 05:52 PM
Debbie,

I guess I should ask you if this is a rant or reason, LOL, I personally found your last opinion highly inflammatory.

For the record I agree with some medical opinions (not editorial boards) and find myself thinking not only about my own experience, but that of MANY other women diagnosed at a young age with aggressive cancers.

I think Dr. Weiss has a good summary:

http://www.breastcancer.org/opinion/mamm_guidelines/letter.jsp

Debbie L.
11-20-2009, 06:52 PM
Margerie said:
I guess I should ask you if this is a rant or reason, LOL, I personally found your last opinion highly inflammatory.

It was not MY opinion (although it reflects and agrees with my opinion). It was in THE NEW YORK TIMES, hardly a publication lacking respect nor track record for excellent and accurate reporting.
Debbie Laxague

Margerie
11-20-2009, 07:05 PM
I was talking about your personal opinion about what is considered rants, reason and the like:

"I'm not even going to try talk about this, with the level of bias, anger, and fear that abounds here right now. But I WILL sign my name (laughing). I see that the few who have tried to inject some reason into these rants haven't signed their name - whether from simple oversight or fear of flaming we won't know"

And in light of Joe's last note, I think we should all tone it down.

Debbie L.
11-20-2009, 07:26 PM
Margerie, I did not post anything political nor inflammatory. I simply said that I supported and agreed with the level-headed NYT editorial. If one agrees with what that editorial said, then the posts here that question and denigrate the motives of the USPSTF, Susan Love, NBCC, BCA, and other respected breast cancer groups - those ARE reactionary and paranoid.

Again, from the closing statement of the NYT editorial:

"There is nothing wrong with a healthy public
debate about mammography within the medical
community and among women who must decide when
and how often to get screened. It should not be
injected into the partisan debate over health care reform."

I have much more to say but am trying to remain calm and rational in this discussion. I do not wish to throw daggers at those who disagree with me. I am open to rational and polite debate. I WELCOME rational and polite debate. But I have not heard from anyone (yet) on this list who is willing to participate in that so I'll bite my tongue and leave it at that. For now.

Debbie Laxague, hoping that there are some (silent?) readers on this list who still have open minds.

Rich66
11-20-2009, 08:02 PM
Was my post inflammatory?

Laurel
11-20-2009, 08:46 PM
Well, if it was, Rich, I recommend Fish Oil, and a host of anti-inflammatory supplements!

I think the discussions are great. I am enjoying the process, personally. As for the Times, well, I've always considered it an over-priced rag, but that's just me. When I lived on Long Island many years ago my boyfriend and I would go to Jones Beach on Sundays with the Times, of course. I'd read through my favorite sections, take a long walk, a dip, and then I was ready to go. My boyfriend loved to bake in the sun, the "bronzed Adonis" I called him, which drove me nuts. I suppose I should give the Times credit for keeping me distracted while he roasted himself.

Has anyone signed the petition over on BreastCancer.org? It is sponsored by Dr. Weiss. There is also a survey regarding the new guidelines.



(http://www.breastcancer.org/utils/survey_request.html)

swimangel72
11-20-2009, 09:26 PM
So Debbie, because I disagree with the NY Times article you quoted and also disagree with Dr. Susan Love - that makes me "reactionary and paranoid" ? I think not.........and most of the women who have responded to this thread seem intelligent and thoughtful - yes they are angry, and they have a right to be so, but certainly not "paranoid".

I am totally dismayed and depressed that doctors on this task force are more like actuarians than healers.........and that they are willing to permit an increase in breast cancer deaths to save money. Still, I AM hopeful that this firestorm of controversy will have a benefit in the long run............that more of our breast cancer fund-raising dollars will go towards real RESEARCH to find the "evidence" that they are basing all these guidelines on...........that scientists will pursue more reliable and safer breast cancer screening tools (cheaper MRI's would be fantastic)..........and that more money will go towards the education of future doctors, especially radiologists, to teach them HOW to properly read the results of these tests to avoid the false-positive dilemna. And finally - that more money will be spent on finding a cure, especially for Stage IV breast cancers. May God's angels watch over and protect all of us.

Debbie L.
11-20-2009, 10:22 PM
So Debbie, because I disagree with the NY Times article you quoted and also disagree with Dr. Susan Love - that makes me "reactionary and paranoid" ?

Not at all. Disagreement and polite debate is how we all learn. We don't necessarily come to agreement, but we learn more about our thoughts and beliefs, and gain an understanding of others thoughts and beliefs also, when we debate politely and with respect.

But to start talking of conspiracy, financial gain, lack of concern for women's health, "death panels" -- as motives for the guidelines that are currently under discussion - yes that's reactionary and paranoid. The panel (USPSTF) took the information available (and they tell us what that information IS, if we want to read their references) and they evaluated both that information and its reliability (how well the studies were done), and they used it to draw their conclusions.

These guidelines are not based on new information. This information (that mammography is not as great as the awareness campaigns would have us believe) has been debated, re-examined, and supplemented by new studies for many years. And still there's controversy about mammography's value in saving lives. Everyone would agree that it's not a very good tool, at best, but it's what we have so we use it.

It has been known for a long time that the solution to breast cancer is much more complex than "early (small) detection", yet the awareness and early-detection campaigns have taken on a life, and a (false) reality of their own, and they have most women believing that if you have a mammogram, you will not die of breast cancer.

There's lots more to say on this subject, but the experts have said it far better than I could. If you're interested, check out the explanations at Susan Love's, NBCC's, or BCA's website. These organizations exist SOLELY to find out how to eradicate breast cancer, or at least to eradicate breast cancer deaths. To disagree with what they say is your right. To imply that they have some ulterior motive (finance or power, for example) is insulting and (again) reactionary and paranoid.

Debbie Laxague

Rich66
11-20-2009, 10:56 PM
With all due respect, Debbie, I would appreciate a response to my post. If you disagree with the points, knock 'em down. No worries.

Sherryg683
11-20-2009, 10:59 PM
Am I ignorant or something for them to say quote "the panel argued that the harms of
mammograms for those women appear to outweigh the benefits.", just sounds plain stupid. I'll take a little radiation and
risk of stress anyday over what I've had to deal with the last 4 years. Trying being diagnosed stage IV..now that's pretty stessfull, you know what... it's deadly too. I had no family history of breast cancer so I guess if what they are saying, I shouldn't have had that mammogram. Until something better comes along that's all we have. I worry about whether they will eventually decide that it's not "worth it" to even treat us stage IV patients properly as we are very expensive to treat..Oh well, I guess I'm just one life to them and that means nothing compared to the whole picture. sherryg

Debbie L.
11-20-2009, 11:24 PM
Rich said:With all due respect, Debbie, I would appreciate a response to my post. If you disagree with the points, knock 'em down. No worries.

Okay. There are about 10 threads on this board about the USPSTF guidelines and I'm not sure which post you're referring to, but I'll copy/paste the one of yours that's closest to this (geographically) and have at it (smile). I just posted on this particular thread at random because I couldn't figure out which was the more active thread and they are all talking about the same things. I'll put your words in black, and mine in blue.

Rich again: Well..that scenario, process and "science" would apply to all screening at any age. But..if a slow growing tumor is found in a young woman, it could be argued it has a greater chance of killing her since it has a greater head start.

Not really. It's not the slow-growing tumors that are the big threat to life. It's the fast-growing ones, which are more likely to metastasize, perhaps even from day 1 (figuratively speaking) in their life cycle. And those are the very tumors that are LEAST likely to be found by mammography. They are more likely to found as "interval" tumors, between mammograms, noticed by the woman (or man) or her (his) partner in the course of daily life. They are typically the ones at work when you hear of a tumor springing up within a month or two of a "clear" mammogram. Yes, sometimes mammograms miss cancers but sometimes cancers grow so fast that they literally seem to appear within months - and unless one is having mammograms every few months or the timing of one's yearly mammogram is lucky - mammography is not going to help save lives lost to those aggressive cancers. This is true in all ages of women, and is part of the reason they cannot find a difference in deaths between women screened every year vs. every 2 years. And as you say, these more-aggressive tumors seem to be more common in women under 50, another reason (in addition to breast density) that mammography cannot show evidence of benefit for them.

In fact, it is pretty well established that BC in younger patients tends to be the more aggressive types. More aggressive cancer, undetected..over a longer period of time. Hmmm.

See above. If we're talking about these really aggressive cancers, the time-frame, and/or the size of the primary tumor, is of less significance than the biology of the cancer cells. We do not know nearly enough about this, but we know more than they did 20 years ago.

I remember hearing this thinking about older women years ago. Now it's being played out at the other end of the age bracket.

Not sure what you mean by that, but if you can explain more, I'll respond. You will find studies and/or researchers who do maintain that mammography isn't of benefit to anyone, any age, as far as saving lives. Probably that's a little extreme, but just the fact that they can find evidence to support that stance, in a few studies - shows us what a poor a tool mammography is, especially compared to what the life-saving attributes the awareness and screening campaigns would imply.

That's a logical (I think) way to look at it. And it also fits with people's intuition and years of PSAs. Makes it a hard sell from both angles.

Again - not sure exactly what you're getting at but yes, the issues of screening are somewhat similar, between prostate and breast cancer.

And yeah..mammography is oversold in the sense that it also has significant false negatives. I wonder how many women have taken false assurance from a negative mammo and stopped any self-exam. I forgot..those are unnecessary.

I don't know about stopping self-exam (which they are not exactly saying is "unnecessary" - they are saying that teaching a formal regimen of BSE does not save lives). But I personally know of two women who sat there for months with lumps they were aware of, because they'd had negative mammograms and so felt safe. Now did that make a difference to their outcome? Probably not, maybe so.

But..I'm glad it won't get run up the beancounter's flagpole. Might keep an eye on it anyway.

Always! Keep an eye on everything. Advocate for better answers so we can have fewer deaths. I am bleary-eyed and going to bed now but we can talk more in the morning if you want. I didn't realize you were asking the question about being "inflammatory" of me - it was someone else who accused ME of being inflammatory, not the other way 'round. When I look at the posts, they are just one after the other - no way to tell who's responding to whose post unless it's prefaced that way.

Debbie

Rich66
11-21-2009, 12:10 AM
Thank you for the calm discourse. I agree they don't know everything. And they don't know what treatments in the works now will change the ability to deal with this disease tomorrow.

Futhermore, if it were as simple as cancers that pose no threat or cancers that are untreatable no matter when they are discovered, screening would be irrelevant at any age.
Again..I can see this kind of think at least being floated in older patients with "comorbidities". (I hate that %&^%& word) i have seen frst hand the misjudgement of co-morbidities as well.
Avoiding early detection in younger patients is like saying they have either harmless cancer or cancer that won't benefit from early detection/early treatment. I'd have to see something that spells that out convincingly. And even then it would be based on the equations and paradigms of the past. Let's give young women, and their future treatment teams, the benefit of the doubt. Maybe some better diagnostic tools could help too:

Thermography preferable to mammography
Women with a continued interest in breast cancer screening (http://www.naturalnews.com/breast_cancer_screening.html) would do well to choose thermography (http://www.naturalnews.com/thermography.html) rather than mammography. Thermography utilizes digital infrared imaging, a safe detection method that analyzes body heat levels in and around the breasts. By analyzing blood vessel circulation and metabolic changes that typically accompany the onset of tumorous growths, thermography is arguably the most effective, accurate, and safest breast cancer detection method.

Her2-ers here were battling against statistical odds long before T-DM1 was a glimmer in anyone's eye.
In terms of the sell of the idea, I was suggesting the general public is going to have some difficulty switching from a being drilled on the importance of mammograms to being told they don't benefit younger patients.
But what do I know? And what will they know tomorrow?
Here's what I saw today:

Cancer Epidemiol Biomarkers Prev. (http://javascript%3Cb%3E%3C/b%3E:AL_get%28this,%20%27jour%27,%20%27Cancer%20Ep idemiol%20Biomarkers%20Prev.%27%29;) 2009 Mar;18(3):718-25. Epub 2009 Mar 3.
Cost-effectiveness analysis of mammography and clinical breast examination strategies: a comparison with current guidelines.

Ahern CH (http://www.ncbi.nlm.nih.gov/pubmed?term=%22Ahern%20CH%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsP anel.Pubmed_RVAbstract), Shen Y (http://www.ncbi.nlm.nih.gov/pubmed?term=%22Shen%20Y%22%5BAuthor%5D&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsP anel.Pubmed_RVAbstract).
Department of Medicine, The Dan L. Duncan Cancer Center at Baylor College of Medicine, Houston, TX 77030-4009, USA.
PURPOSE: Breast cancer screening by mammography and clinical breast exam are commonly used for early tumor detection. Previous cost-effectiveness studies considered mammography alone or did not account for all relevant costs. In this study, we assessed the cost-effectiveness of screening schedules recommended by three major cancer organizations and compared them with alternative strategies. We considered costs of screening examinations, subsequent work-up, biopsy, and treatment interventions after diagnosis. METHODS: We used a microsimulation model to generate women's life histories, and assessed screening and treatment effects on survival. Using statistical models, we accounted for age-specific incidence, preclinical disease duration, and age-specific sensitivity and specificity for each screening modality. The outcomes of interest were quality-adjusted life years (QALY) saved and total costs with a 3% annual discount rate. Incremental cost-effectiveness ratios were used to compare strategies. Sensitivity analyses were done by varying some of the assumptions. RESULTS: Compared with guidelines from the National Cancer Institute and the U.S. Preventive Services Task Force, alternative strategies were more efficient. Mammography and clinical breast exam in alternating years from ages 40 to 79 years was a cost-effective alternative compared with the guidelines, costing $35,500 per QALY saved compared with no screening. The American Cancer Society guideline was the most effective and the most expensive, costing over $680,000 for an added QALY compared with the above alternative. CONCLUSION: Screening strategies with lower costs and benefits comparable with those currently recommended should be considered for implementation in practice and for future guidelines.

PMID: 19258473 [PubMed - indexed for MEDLINE]

hutchibk
11-21-2009, 01:02 AM
"It was in THE NEW YORK TIMES, hardly a publication lacking respect nor track record for excellent and accurate reporting."

With a well documented recent history of continued plagiarism and fabrication, I find it hard to consider the NYT a credible source about much of anything.

UPDATE, 11/21/2009, 4:30pm CST:
Notice in my above sentence I did not accuse the NYT of political bias. I referenced the well documented plagiarism and fabrication in their reporting. No need for anyone (2 in particular in other threads) to fallaciously connect my opinion of the NYT to incoherent posts about the perceived political bias of Fox News... wow. Odd. Interesting. Silly.

hutchibk
11-21-2009, 01:11 AM
That said, of course everyone wants better diagnostics and wants to keep an eye toward innovation, but we aren't there yet and mammo's save lives. I am always suspect when reconsidering testing recommendations or proposing not testing because of the "emotional toll" that diagnostics might take due to false positives. I would rather have a lifetime of false positives than not have access to the test that ACTUALLY gave me an ACCURATE positive at age 44 and afforded me at least an extra 6 years as of this week... and still counting.

It's not surprising that this is getting very emotional for women, as this week it seems we are experiencing an all out assault on women's health.

The same Task Force also cited new recommendations to pull back heart health screening for women based on data ending in 2002, ignoring newer studies that seemed to fly in the face of the recommendation to pull back from current heart health screening practices.

And then to hear today about the new pull back for pap smear/exam recommendations to every two years beginning at age 21.

There is a MUCH bigger picture here and I won't pretend that there isn't. This is all very suspect, and the timing is tremendously curious.

swimangel72
11-21-2009, 07:58 AM
Debbie, Rich, Hutch, Sherry, Rhonda - and everyone else who has taken the time to do research and post replies - I want to thank you all, no matter what your opinion, for your intelligent words.......for your caring concern and for helping me to keep an open mind. It's interesting to me that my mother (85 years old like a Timex - takes a licking but keeps on ticking) has never had a mammo or a pap smear. My MIL also never had a mammo - and has never been to an ob/gyn since giving birth to her last child 44 years ago. I also recall a study showing that many small bc tumors really "disappear" over time........but even so, I reassure myself that I didn't get overtreated for my small .9cm Stage 1 tumor because it was NOT in that category since it was Her2++++ . I think in many ways, the new guidelines and the firestorm is has created will bring renewed attention to the problem we ourselves have been addressing for so long...........why are the rates of death from BC not decreasing? And ultimately, as I said before, I hope that our donations will go towards PURE research towards better screening methods (where's Dr. McCoy and his tri-corder when we need it?) and towards a cure for ALL cancers. Thank you again - and have a good weekend everyone.
http://her2support.org/vbulletin/picture.php?albumid=64&pictureid=118

StephN
11-21-2009, 02:56 PM
Dear Kathy -
What a great picture. And I love the "Stand Together" message.

To your question on the NOT decreasing death rate. We also have an increasing diagnosis rate and higher in younger women, to counterbalance the lives saved by newer and more individualized treatments.

It has also been proven that the beast is much more complicated than thought 5, 10 or 15 years ago. I can't count how many times I heard "the more we find out about breast cancer, the less we KNOW" at the AACR conference last April.

If the researchers could invent bionic breasts, might that solve the breast health screening questions?
Wonder where on the genetic thread this would go?

WolverineFan
11-21-2009, 06:24 PM
Debbie,

While I respect the right for each person to voice their opinion, I obviously don't share the same opinion as you. Honestly, it is amazing to me that anyone who has or had bc (or loves someone that has or had bc), particularly someone with HER2 bc, could be in support of these guidelines.

While my situation pales in comparison to many who have posted on this board already, had I waited until age 50, I would be dead. I have no history of bc in my family and was in, what I thought, great health. While my lump was found on my own because I hadn't even reached the age of 40, it would have been found on one when the time came because it did show up. I have two small children that I absolutely have to be here for, and I am grateful every day that mine was caught at an early stage. I am also now thankful that I do have bc, because my sisters, ages 47, 46 and 33 will meet the new guidelines and be able to have the necessary screening to at least offer a chance at catching it early should they develop this wretched disease.

I realize there is no guarantee that the mamms will find cancer, and I also understand that it can yield false results, but the flip side is it also DOES find cancer and as a result, DOES saves lives. Maybe not to the degree that the insurance companies would like, but try telling that to the women and their families whose mamm showed the cancer.

I was one that didn't sign my name on an earlier post, which is odd because I normally do sign my name. The only reason I could think of that I didn't sign it is because I was so flaming mad after reading Dr. Love's blog.

Gladly...here is my name,

Hayley Rose

Jackie07
11-21-2009, 07:18 PM
Found this statement on an Irish Health care site. I think it is the type of information most of us are familiar with. Mammogram had contributed to a 2.3% annual decline for 'all' women and had greater decrease for women 50 years and older.

"A mammogram is a safe, low-dose X-ray that can detect irregularities in the breast, sometimes even before you or your doctor can feel a lump. A high-quality mammography has the ability to detect cancer before the physical signals are present. Multiple studies have shown that they save lives and increase treatment options. Women that have their annual mammogram screening are 30% less likely to die from breast cancer when compared to unscreened women. From 1990-2000, mortality rates declined 2.3% per year for all women and an even greater decrease per year for women 50 years and under. This is the result of both early detection and improved treatment."

Why has it suddently become 'unsafe', 'unreliable', and 'do it only when you feel a lump' is hard to understand. I will welcome any new, improved method whether or not it was developed by special interest group or benefit certain promoter. But before we've got another reliable (and hopefully as inexpensive as mammogram) method, I would think it's prudent to continue the type of guideline that encourages early detection. Because it saves lives. '30% less likely to die' is not a statement to be ignored.