low fat diet cuts bc relapse according to NCI's WINS study...

[RobinP]

Public release date: 16-Dec-2006

Reduced dietary fat intake may decrease breast cancer recurrence

http://www.eurekalert.org/pub_releases/2006-12/jotn-df121406.php

[RobinP]

http://health.dailynewscentral.com/content/view/779/63

[RobinP]

Look at the HUGE benefit of having a low fat diet for the hormonal negative breast cancer which most her2 positives are. The relapse reduction is substantial. Wow. Let's all get on the low, low, low fat...



http://www.iht.com/articles/ap/2006/12/16/america/NA_GEN_US_Diet_Breast_Cancer.php

[R.B.]

There are those that would argue that type of fat intake is very important as well.

For those tha have not looked you might like to use the search option click search on the bar above and enter omega three omega six etc.

There could be many factors involved in fat the reported fat reduction effect, trans fats, omega six, other factors associated with animal fats etc.


RB

[AlaskaAngel]

I suspect that when people reduce the fat severely in their diet they end up being forced into taking in a better balance of fats... and may additionally be taking in mostly fats that more often do not have synthetic toxins like hormones and pesticides added to them. For me an interesting question is, why would ER/PR negatives get more benefit from the fat reduction than other bc categories...?

[Becky]

I saw this study presented at both ASCO and SABCS. At ASCO, I was with Kim from CT (Mamacze) and we both asked a question. Kim asked how (on earth) you could follow a diet so low in fat like this one. The answer is that you have to be a vegan. Fat can only come from vegetable or nuts (and oils). I asked if they were seeing results from a better balancing of omega 3s and 6s but the investigator said that is pausible but not probable and DID say that it should be studied.


The investigator said that the results were surprising as one would assume that it would help hormone positives more. Their findings (with hormone negative or having at least one receptor negative) only creates guesses. The guesses mentioned are other receptors come into play with hormone negatives such as IGFR and other downstream insulin reactions as well as that weight loss from this diet can help regulate insulin resistance. Besides a new study to study balancing fatty acids, they would like to study doing this diet with exercise (of which we ALSO know from that study that it also more greatly benefits hormone negative women) and see if there are syngeristic effects.

[RobinP]

I agree with Becky AA, that the reason hormonal positives don't benefit as much is probably because of the IGFR. It may be that hormonal positives do not have tumors that are IGFR+. I know that my tumor tested IGFR+ and I was horomonal negative, so I would benefit from lower insulin level= less calories, less carbs, and more exercise.

[RhondaH]

transporter gene expression.

While reading up on IGFR, I found this article. For those of you who don't know what a Ketogenic Diet is, it is an "alternative medicine" diet that is supposed to help epileptics (my dad sent it to me years ago as I am epileptic, but being that I am allergic to fowl and USED to be until recently, allergic to fish, my diet only consisted of red meat (AND lots of sugar)...hmmm. I'm ER/PR-. Take care and God bless.

Rhonda

http://cat.inist.fr/?aModele=afficheN&cpsidt=14829821