rsr-13 details?

[mkrny]

All,
looking for summary data dump on rsr13 status and effectivity. Christine & Joe said Al is the man with the info on this but we'll take it from any source.
Thanks, m&k

[mts]

Once the page opens, go to item #4
(I presume this is what your looking for)


http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=PureSearch&db=pubmed&details_term=%28%28%22efaproxiral%22%5BTIAB%5D%20N OT%20Medline%5BSB%5D%29%20OR%20%22efaproxiral%22%5 BSubstance%20Name%5D%20OR%20RSR13%5BText%20Word%5D %29%20AND%20%22brain%20metastases%22%5BAll%20Field s%5D%20NOT%20allosteric%5BTI%5D (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=PureSearch&db=pubmed&details_term=%28%28%22efaproxiral%22%5BTIAB%5D%20N OT%20Medline%5BSB%5D%29%20OR%20%22efaproxiral%22%5 BSubstance%20Name%5D%20OR%20RSR13%5BText%20Word%5D %29%20AND%20%22brain%20metastases%22%5BAll%20Field s%5D%20NOT%20allosteric%5BTI%5D)


Also, there is quite a bit of info regarding rsr13 (efaproxiral/Efaproxyn) on
www.lungcanceronline.org (http://www.lungcanceronline.org)

maria

[mkrny]

Unless I missed something rsr13 is still in clinical trial. #4 was dated Dec 2005. If so, why is approval taking so long? I haven't seen any negative feedback on rsr13.
Thanks
m&k

[mkrny]

MADUBOIS63 (MADUBOIS63@aol.com) hoooked me up with info off-forum. I spoke with someone running local trial and the parameters rule my Maryann out. No one who has had or will have brain surgery can be included. I'm sure that really restricts their pool of eligible folks.
If anyone knows different please let us know.
FYI-
http://www.allos.com/Amend/images/ENRICH%20US%20website%208-10.pdf

m&k

[mkrny]

I will try calling the company directly but I was told that Allos won't include anyone who has had or will have brain surgery either conventional resection or radiosurgery.

I spoke about this with Dr Karen Hoffman who is organizing the trial local to us at the following hospitals (see link eariler in this thread for full list):

~~~~~~~~~~~~
Eastchester Center for Cancer Care
Bronx, NY
Principal Investigator: Dr. Fabio Volterra
Contact: Karen Hoffman
718.543.8678
karen@eastchestercenter.com

Suny Downstate Medical CenterBrooklyn, NY
Principal Investigator: Dr. Marvin Rotman
Contact: Joanna Mikhail-Powe or Fazal Hussain
718.732.4000 or 718.270.2181
joanna@eastchestercenter.com
fazal.hussain@downstate.edu
~~~~~~~~~~~~~~~~~~~~~~