Oleic Acid/Olive oil/HER2 suppression

[StephN]

I see that a snippet of an article has been posted below on this same subject with some posts back and forth - good interaction and interest!

I finally had a chance to study the science behind the claim to see what else I could learn about the actual process of downregulating the HER2 overexpression in my body with the oleic acids.

The link takes you to the Annals of Oncology where the whole report is published. Easy to download the PDF - and if you have a problem they have a help button and free download of Adobe Acrobat Reader.

Makes for fascinating reading, and there are actual photos of breast cancer cells that have been exposed to the oleic acid and then also to trastuzumab (Herceptin). You can ACTUALLY see the suppression working.

The article also goes into the other pathways involved with HER2 downregulation, cell apoptosis, kinase inhibitors etc. SO complex our bodies are!


http://annonc.oupjournals.org/cgi/reprint/mdi090v1

[Kristen]

Thank you, I look forward to reading it. k

[StephN]

Some posters on this board as well as the Articles of Interest area were wondering what your doctors would say.

Here is a quote from mine via email today:

"These researchers (Lupu's group in Chicago) have been on the trail of something called fatty acid synthase for years as a player in breast cancer, and they now appear to have some results that could be tested in a clinical setting. Let's hear it for olive oil!"

Let's hope they get a trial approved soon! There will be a lineup for participants, I am sure.

Going for my Herceptin tomorrow after having a nice bit of olive oil with my meal this evening. (In grated carrot/red cabbage slaw, with mild balsamic vinegar and sea salt.)

[*_Trudy_*]

Thank You Steph for this great information. Do you know how much olive oil
is recommended on a daily basis?

Thanks,

Trudy

[*_Meg_*]

I would also be very interested in how much olive oil you eat a day.

Thanks for finding the article and posting it; several pages of it are actually comprehensible, and it is great that Western researchers are finally starting to look at food.

[*_Kim in DC_*]

Thank you for the link to the actual study. I find your posts to be very informative.