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Paul
04-21-2004, 12:52 AM
Hi Linda,

Aromasin™/exemestane is known as an "aromatase inhibitor" and is a form of anti-estrogen breast cancer drug treatment. It is generally used for women who have breast cancer that is estrogen-positive or progesterone positive or both estrogen and progesterone positive. The concept is that without estrogen/progesterone, the cancer will be deprived of a critical element required for it proliferation.

Aromatase inhibitors work by blocking the enyzme aromatase in a woman's body. Aromatase is a critical enyzme used by a woman's body to produce estrogen. Whereas tamoxifen blocks the estrogen receptor on cancer cells, aromatase inhibitors reduce the overall presence of estrogen in a woman's body.

Above, I suggested that Lyn get retested to determine if she really is ER+ or PR+ . If her first test was truly accurate, she could very well be the beneficiary of an unintended result of the drug. Regardless of the explanation, I believe Lyn will take those fantastic results to the bank.

lindaw
04-21-2004, 08:13 AM
Dear Paul
Thanks for this information. I ma having my biopsy / excision next week and will test that bit for her2 ( I am her2 obviously) and er/pr again - so this may be timely information.

love
linda